Genomic Solutions launches plate arraying technology
the BioRobotics MicroGrid II and the GeneMachines OmniGrid Accent.
This technology allows the production of DNA and protein
microarrays in 96 and 384-well microplates allowing the printing of
over 1000 features within an individual well in a 96-well
microplate.
This multiplexed approach enables researchers to drive microarray production into new application areas such as micro ELISAs, diagnostic arrays and other protein-protein studies in a higher throughput format to that previously available.
An example is illustrated on the BioRobotics MicroGrid II, which has the capacity to hold 16 microplates. This enables a researcher to improve assay production by a factor of fifty compared to standard slide production methods. The GeneMachines OmniGrid Accent is capable of holding 6 microplates and therefore offers a similar improvement in productivity.
Dr Jeremy Clarke, global product manager for Genomic Solutions told DrugResearcher.com: "We launched this product as a response to requests from protein array customers and core labs which wanted the process of arraying into plates made more easier."
Genomic Solutions software enables the user to visualise and define the array layout prior to the start of a printing run allowing total control. In addition the proprietary Soft Touch feature allows printing onto the surface of the well, particularly useful when arraying onto a coated surface.
Clarke said: "Drug discovery wise, this technology would be suitable for microELISA, screening cell lysate to protein libraries, and testing genomic arrays to a range of hyb probes in a microplate format."
A library of definitions for most common microplates is also available in the software allowing set up of arrays into the users choice of plates.
Initially this technology is available as part of a new purchase, or can be provided as an upgrade kit to existing MicroGrid II and OmniGrid Accent customers.
Genomic Solutions' applications can assist on microarray design and spotting technique. The Plate Arraying technology option is suitable for researchers needing to multiplex assays in the microplate format.
"This technology is aimed towards core labs, diagnostic array producers, protein array lab and ELISA researchers looking to increase assay throughput," Clarke added.
"Similar technology currently on the market involves that which can work to this spot density. I'm specifically talking about the piezo market. Our advantage is that pins are much easier to use, easier to clean and less prone to blockages and drop-out."
On commenting on the state of the microarray market, Clarke mentioned that it was currently in a period of growth.
"We estimate at a rate of approximately 6-7 per cent. The main industry drive stems from new applications that need array production. These include RNAi, SNP, Array CGH, protein arrays and protein moiety arrays."
