Wyatt releases powerful light scattering detector
Light Scattering (MALS) Detector range, boasting twice the signal
to noise ratio and 100x the dynamic range of previous Wyatt's
miniDAWN instruments.
The leap in technical capabilities means measurement of smaller molecules at lower concentrations than ever before is now possible.
This is achieved through a process that allows each analog signal (one for each of the three angles) is processed by its own Digital Signal Processing (DSP) integrated circuit with 24-bit digital conversion for extremely high signal resolution.
In addition, four auxiliary analog inputs (with their own DSP circuits) are available for interfacing to external detectors, such as DRI, UV, PDA, etc.
The detector also records the temperature, laser power, and forward monitor signal - valuable "extra" for studying samples that absorb light.
MALS is a non-invasive technique for characterising macromolecules and a wide range of particles in solution. In contrast to most methods for characterisation, it does not require outside calibration standards.
Current methods involve the estimation of these quantities all of the time. But when these products that are injected or injested, more accurate method of quantifying these measurements are needed. Molar mass and size are physical characteristics crucial for healthcare products.
Optional features may be added such as the embedded COMET system, which automatically cleans the flow cell in situ.
This insures that your system produces the same high quality data day after day, with NO downtime.
In addition, the embedded WyattQELS allows simultaneous online measurement of hydrodynamic radius.
This improves the resolution of the size distribution measurements by over an order of magnitude compared to batch QELS.
The miniDAWN TREOS can work seamlessly with all other >Wyatt instruments, such as the ViscoStar differential bridge viscometer, via the network or USB interfaces.
It has the capability of taking signals from a variety of third party instruments, such as UV absorption, DRI, IR absorption, evaporative light scattering or photodiode array detectors.
Advanced research in pharmaceutics and biotechnology has resulted in the market for detectors of this nature to become much in demand.
Most of the molecules of interest in these fields are macromolecules like proteins, hyaluronic acid and haemoglobin, not to mention nanoparticles like liposomes or viruses, which can be used as drug-delivery vehicles.
Wyatt will be showcasing the miniDAWN TREOS on booth 5.1 H39 at ACHEMA 2006 in Frankfurt, Germany, May 15-19.
