CRO partners with humanized model developer to advance liver disease research

Seventh Wave Laboratories and Yecuris Corporation have announced an exclusive collaboration through which the CRO will provide various services.

Seventh Wave Laboratories is a consulting-based contract research organization (CRO) located in Maryland Heights, Mo.

The company provides services for discovery and preclinical drug development, including PK/ADME, bioanalysis, toxicology and pathology services.

Through the recently announced partnership, the CRO will provide services related to hepatitis B virus and C virus pharmacology studies using the Yecuris liver humanized FRG KO model.

Seventh Wave will also provide toxicology, metabolism and other pharmacology services using models developed by Yecuris Corporation. 

Portland, OR-based Yecuris was founded in 2007 to commercialize the FRG KO mouse technology and has been validating viremic and gene expression models for more than a year with Seventh Wave.

"Both companies are committed to supporting the partnership as long as it makes sense for our clients. In our pre-launch period, we’ve successfully supported a number of client-sponsored studies, and we believe there is a long future ahead with this partnership," Joe Flynn, Chief Commercial Officer at Seventh Wave, told Outsourcing-Pharma.com.

"Both Seventh Wave and Yecuris have invested significantly in R&D to develop and validate this model — we’re past the theoretical stage and have proven the concept internally and also with client-sponsored studies," Flynn added. "We’ve also spent a great deal of time with prospective clients in the pre-launch period to really understand what they are looking for in terms of study design and key endpoints."