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The Performance of PROSOLV® EASYtab SP in 4 Medium-Dose, Direct Compression Formulations

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The-Performance-of-PROSOLV-R-EASYtab-SP-in-4-Medium-Dose-Direct-Compression-Formulations.png

In the present study, the performance of PROSOLV® EASYtab SP was tested in four DC formulations with different model APIs. Each of the selected APIs presented a particular challenge in terms of producing tablets with suitable hardness, weight uniformity, content uniformity and/or reliable dissolution profiles.

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The aim of this study was to investigate the disintegration behavior of croscarmellose sodium (CCS), sodium starch glycolate (SSG) and crospovidone (PVPP).