Drug delivery, formulation

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Content provided by Univar Solutions USA | 07-Oct-2024 | Product Brochure

In partnership with our industry-leading supplier partners, Univar Solutions Pharmaceutical Ingredients is proud to introduce Powering Healthy Tomorrows.

Reliability, scale, and security of supply

Content provided by Univar Solutions USA | 28-Aug-2024 | Product Brochure

Univar Solutions Pharmaceutical Ingredients is proud to offer one of the most expansive portfolios of 15,000+ products, including high-purity solvents,...

Increasing the Bioavailability of Oncology Drugs

Content provided by Lonza Small Molecules | 13-Nov-2023 | White Paper

Oral tyrosine kinase inhibitors (TKIs) are a class of cancer drugs that can be highly susceptible to issues with solubility in the gastrointestinal tract

Let your Senses Guide you into the world of Art & Science: Meet with Funtrition & Sofgen during Supply Side West 2023

Procaps Group, a leading integrated LatAm healthcare and pharmaceutical services company,

Addressing Challenges with Clinical In-Use Testing

Content provided by Lonza | 12-Oct-2023 | White Paper

Lonza Drug Product expert Léa Sorret PhD explores Clinical In-Use Testing of Biotherapeutics in this white paper. Léa shares her expertise and describes...

PBPK modeling that saves you time and money

Content provided by Lonza Small Molecules | 09-Oct-2023 | White Paper

Understanding pharmacokinetic behaviors ahead of later-stage development means making informed decisions earlier. This enhanced capability helps your drug...

Manufacturing Drugs with Highly Potent APIs

Content provided by Altasciences | 28-Sep-2023 | White Paper

In this issue of The Altascientist, we examine the critical considerations for the safe and compliant manufacture of drugs with highly potent APIs (HPAPIs),...

In vitro evaluation of the gastrointestinal delivery of acid-sensitive pancrelipase in a next generation enteric capsule using an exocrine pancreatic insufficiency disease model

Content provided by Lonza Capsules & Health Ingredients | 27-Sep-2023 | White Paper

International Journal of Pharmceutics: In Vitro: The dissolution characteristics of five capsules (Next Generation Enteric [NGE], Vcaps® Enteric [VCE],...

ReciBioPharm - An optimized Plasmid DNA platform to accelerate the path to clinic and commercialization

Recipharm AB | Recorded the 14-Sep-2023 | Webinar

Assessing key parameters of the upstream process to achieve high titer while maintaining desired integrity
Customizing the downstream process to...

How enhancing equipment reliability supports quality, efficiency, and operational excellence

Content provided by Bora Pharmaceuticals | 10-Aug-2023 | White Paper

Successfully manufacturing a drug product requires people, proper equipment, and materials. It’s the classic three-legged stool analogy. Even with well-trained...

Drug Solubility and the Need for Speed

Content provided by Lonza Small Molecules | 28-Mar-2023 | White Paper

A growing number of new chemical entities are highly insoluble, leading to problems with bioavailability. Drug manufacturers therefore have to find ways...

2023 State of Clinical Trial Technology Report

Content provided by Florence Healthcare | 01-Mar-2023 | Insight Guide

Discover the trends shaping clinical trial technology in 2023, from Site Enablement to eISFs, integrations, and site-sponsor collaboration. This report...

Tackling Early Phase Development with First-In-Human Study Solutions

Content provided by Altasciences | 25-Oct-2022 | White Paper

Bringing new drugs to market, from lead candidate selection through preclinical testing, to clinical proof of concept, is a complex, time-consuming, and...

The Complexities of Ophthalmic Drug Development

Content provided by Altasciences | 04-Oct-2022 | White Paper

Ophthalmic drug development comes with a unique set of challenges that can be mitigated by working with an end-to-end solution provider with regulatory...

Seasonal Vaccine Manufacturing

Content provided by Baxter BioPharma Solutions | 13-Jul-2022 | White Paper

The production of seasonal vaccines, such as those for influenza, presents unique challenges to manufacturers due to the necessary time constraints resulting...

Formulation Effects on Tablet Surface Properties and Film Coating Adhesion

Content provided by JRS PHARMA | 01-Jul-2022 | White Paper

The aim of this study was to investigate the influence of different commonly applied lubricants and disintegrants on tablet surface and film coating adhesion....

Flexible Filling Solution for CMOs

Content provided by Single Use Support GmBH | 18-May-2022 | Insight Guide

Achieving flexibility requires modularity of technologies.

CMOs and CDMOs aspire to be flexible for multiple applications. Efficient automated...

Nanomilling for Better Solubility and Bioavailability

Content provided by Altasciences | 07-Apr-2022 | White Paper

40% of marketed drugs and 90% of active pharmaceutical ingredients (APIs) are poorly water-soluble. Nanomilling is a proven technique that can overcome...

Eastern & Western Manufacturing Solutions

Content provided by Piramal Pharma Solutions | 15-Mar-2022 | White Paper

The best manufacturing site for a product can change throughout the life cycle. When bringing new drugs to market, biopharma companies may benefit from...

How Formulation Development Affects Manufacturing

Content provided by Catalent | 24-Feb-2022 | Insight Guide

Due to advances in technology and increased development of parenteral drugs, one of the fastest-growing choices for drug delivery in the pharmaceutical...

Maximizing Drug Formulation for First-In-Human Trials

Content provided by Altasciences | 13-Dec-2021 | Case Study

The manufacture of a drug product for clinical trials is of critical importance. The formulation, manufacturing, and assessment of a drug candidate during...

Flexibility and capability in pre-filled syringes

Content provided by Curia | 15-Nov-2021 | White Paper

Pre-filled syringes have risen in popularity in recent years but the pandemic’s impact on drug development, manufacturing and patient care has created...

Overcoming Solubility Challenges with Liquid-Filled Capsules

Content provided by Altasciences | 28-Sep-2021 | White Paper

Poorly soluble molecules comprise more than 70% of the small molecule products entering the drug development pipeline today, and are difficult to formulate...

A Better Approach, for Better Pain Trials

Content provided by Signant Health | 27-Sep-2021 | White Paper

Pain studies face unique challenges. For one, pain severity can only be truly assessed by the patients themselves. The controlled substances that are often...

Bioavailability Enhancement Techniques to Improve Patients' Lives

Content provided by Piramal Pharma Solutions | 16-Sep-2021 | White Paper

Oral bioavailability is a constant challenge for developers of new chemical entities. Low solubility and permeability often reduce the fraction of an orally...

Transforming Clinical Development

Content provided by PerkinElmer | 01-May-2021 | White Paper

The estimated cost of bringing a drug to market in the U.S. according to JAMA is $1 billion.1 The extreme cost of clinical trials urge biopharmaceutical,...

Q&A: Effective Drug Product Process Development

Content provided by Catalent | 14-Jan-2021 | Insight Guide

In this Q&A, a Catalent Biologics expert shares his expertise with drug product process development challenges, risks and how to mitigate them, the...

Formulation and development strategies for amorphous solid dispersions

Content provided by Lonza | 17-Sep-2020 | Sponsored Link

A large and increasing fraction of orally administered small molecules in pharma company pipelines have poor oral absorption due to low aqueous solubility...

Accelerated development of first-in-human programs. Lonza’s SimpliFiH® Solutions

Content provided by Lonza | 25-Aug-2020 | Sponsored Link

The presented program is laid out as integrated Drug Substance, Particle Engineering and Drug Product services, enabling drug substance and drug product...

Flow Cytometry Services

Content provided by Q² Solutions | 01-Jun-2020 | Infographic

We are an established leader in flow cytometry services for clinical trials. Our technologies and solutions meet the growing global demand for enhanced...

Outsourcing Analytical Testing for Biologics - A CRO's Perspective

Content provided by Frontage Laboratories | 01-Dec-2019 | White Paper

Biologics are complex large molecules derived from living organisms or manufactured from cells, and they have inherent structural heterogeneity. Indeed,...

How to Avoid Surprises in Small-Molecule Drug Development Programs

Content provided by Frontage Laboratories | 01-Oct-2019 | White Paper

Over the years, the pharmaceutical industry has made steady progress in improving the safety of drugs in development. Consequently, in 2015, only 14 percent...

Validating The Simoa Technology

Content provided by Frontage Laboratories | 01-Oct-2019 | White Paper

Frontage is the first and only laboratory to validate Quanterix’ Simoa HD1 Analyzer for performing immunoassays. Most of the advanced instruments used...

The Truth about Physician Referrals and Clinical Trials

Content provided by BBK Worldwide | 24-Jul-2019 | White Paper

Despite growing evidence, the myth that physicians won’t refer patients to clinical trials persists, perpetuated by the belief that they fear losing their...

Stability Testing As a Quality Control Measure

Content provided by Frontage Laboratories | 19-Jun-2019 | White Paper

Stability testing is, in essence, a quality control process and is there¬fore a vital component of every phase of clinical development for both large and...

Survey Report: State of the global pharmaceutical contract services industry 2018

Content provided by William Reed | 11-Jul-2018 | Research Study

In May 2018 Outsourcing-Pharma.com, in association with InnovoCommerce, conducted its second annual ‘state of the industry’ survey on its user base of...

Marken Delivers Compassionate Use Dose of Emergency Medication to Critical Pediatric Patient

Content provided by Marken | 26-Jun-2018 | Case Study

A desperate mother in Germany urged her team of doctors to reach out to a Marken client on behalf of her two year old girl. The child was battling leukemia...

Lyophilization Scale-Up and Tech Transfer

Content provided by Baxter BioPharma Solutions | 12-Mar-2018 | White Paper

There are few challenges when increasing the scale of production for a solution formulation, but the challenges drastically increase when the formulation...

Process Development for Lyophilized Products

Content provided by Baxter BioPharma Solutions | 30-Oct-2017 | Application Note

Baxter approaches formulation and process development with the intention of identifying the failure points for the product. Knowing where the product fails...

UPLC Analysis of Methoxy & 2-Hydroxypropoxy in Hypromellose

Content provided by SGS Life Science Services | 25-Apr-2016 | White Paper

Because of its use in the pharmaceutical and food industries, the USP has established standards relating to the amount of methoxyl and 2-hydroxypropoxyl...

Article on Viral Clearance for Biopharmaceuticals

Content provided by Catalent | 31-Aug-2015 | White Paper

Viral clearance studies are mandated prior to entering clinical trials and for commercial launch of biopharmaceuticals.  These studies are a key component...

Optimize Your Sponsor-CRO Relationship

Content provided by SGS Life Science Services | 20-Apr-2015 | White Paper

Within the pharmaceutical industry, there are six dominant methods used to model outsourcing strategy. This white paper details how a hybrid strategy can...

The whole blood assay: Detection of broad spectrum of pyrogens & examples of medical device testing

Merck KGaA, Darmstadt, Germany | Recorded the 09-Apr-2015 | Webinar

Pyrogens in pharmaceuticals, medical devices, biotherapeutics and cosmetics can cause fevers in humans and are potentially life-threatening. Yet standard...