New database for APIs

Pharmaceutical Substances has become one of the main reference sources for those wishing to screen references to drugs before turning to more detailed primary literature, such as the original patent application or the original research paper. The new version sits alongside the existing paper and CD formats.

The database provides a compendium of some 2,300 APIs, including trade data, and approximately 8,200 reaction schemes of interest to the chemical and pharmaceutical industries. The ingredients are searchable and will be updated twice a year with approximately 50 new ingredients. It covers compounds going back to 1957.

It covers all substances contained in drugs currently on the market, and provides important basic information for chemists working in the pharmaceutical industry, claims Thieme.

For each active pharmaceutical ingredient, reaction schemes for the most important ways of synthesis are available. Starting substances, intermediates and active ingredients are structure-searchable, and reactants and products are structure-searchable with a single reaction query.

STN​ is run by FIZ Karlsruhe, a non-profit scientific service institution.