Aureus release GPCR, interaction and channel database
ADME/Drug-Drug Interactions has been released by Aureus Pharma who
believe this system will prove invaluable in identifying,
validating and prioritise new targets and ligands for drug
discovery.
The AurSCOPE database provides exhaustive channel and biological information related to specific drug targets (G-Protein Coupled Receptors and Ion Channels) and pharmaceutical topics such as ADME/Drug-Drug Interactions.
These AurSCOPE database has been upgraded to include additional literature and patents. Additional search capabilities can be accessed via a web-based interface. Chemists and biologists can use this system to discover safer and more specific drugs developing proprietary strategies based on 'chemogenomics' concepts.
Primarily aimed at medicinal chemists, biologists and chemoinformaticians, drug discovery project leaders in pharma and biotech R & D, the databases are particularly well-suited for chemical library focusing, Designing chemical libraries for a given target family, increasing speed of lead optimization and allow prioritization of projects at an earlier stage.
A spokeswoman for Aureus Pharma told DrugResearcher.com: "We identified a gap in the market where scientific literature was a source for data in which the individual researcher needed to read all the data and gather together."
"This was not easily accessible within a computerized system and also in structured manner. We were looking to fill this gap to help accelerate drug discovery."
Currently similar databases on the market include Jubilant, Sertanty & GVK. However the spokeswoman was quick to point out that Aureus' databases offered both biological and chemical data for a larger range of targets.
"In addition our system is a relational system. In terms of biological responses we include both in vivo and in vitro data," she added.
In January 2003 and November 2002, Aureus Pharma entered into a multi-years agreement with Roche and Aventis respectively giving access to its chemical biology database on G Protein-Coupled Receptors (GPCRs).
