FDA's approval of Sanofi-Aventis' Eloxatin (oxaliplatin) is
unlikely to increase the drug's patient base, but the new
formulation should consolidate Sanofi-Aventis' position as the
largest pharmaceutical firm in...
Bruker Biospin has announced the successful delivery and
installation of its 900MHz NMR magnet, delivering the highest field
strength actively shielded NMR magnet available today.
Biacore International has launched the Biacore T100, a system that
analyses the protein interactions that occur in disease pathways,
selection of drug candidates and decisions on the safety of a
protein therapeutic.
India begins its first ever human clinical trial of an
investigational vaccine candidate designed to treat HIV/AIDS, which
now has a worldwide infection rate of 14,000 every day.
EiRx Therapeutics has entered into an agreement with Merck to carry
out research using its cancer cell assays to use its technology for
identifying drug targets.
Researchers have identified a promising new drug target in their
fight against resilient Staphylococcus bacteria that can be
transmitted to patients in hospitals via contaminated medical
implants.
Hana Biosciences announced today the clinical trial initiation of
PT-523 to evaluate this compound as a single agent in relapsed
non-small cell lung cancer (NSCLC). Lung cancer continues to carry
the poorest prognosis of cancer,...
Speedel Experimenta has announced the completion of its human
micro-dosing studies into renin inhibitors that are set to provide
an effective means of treating hypertension and for protecting end
organs such as the heart and kidneys.
Significant progress toward a more targeted treatment of
Alzheimer's disease was made as scientists targeted an enzyme,
which has a differentiated role and opens up perspectives for new
drugs that have fewer undesired side effects.
Cybio has launched a new flash luminescence reader that improves
throughput and data quality in functional screening of G-Protein
coupled receptors and calcium channels in drug discovery and
research.
GPC Biotech announced the initiation of a Phase I trial with its
anticancer monoclonal antibody, 1D09C3, which has already proved
effective in the treatment of lymphoid tumours including
non-Hodgkin's lymphoma.
Nobex Corporation has been granted two new US patents, which expand
its 'PEGylation' technology of small polyethylene glycols (PEG) for
modifying molecules for improved drug performance.
According to a new report, the number of victims claimed by the
South-East Asian tsunami is likely to rise due to the lack of drugs
in active development for post-tsunami diseases. The report
identified only 87 drugs in active development...
The European monoclonal antibody therapeutics market is set to grow
at a compound annual growth rate (CAGR) of 34.1 per cent to $11.4
billion (€8.7 billion) by 2011. The growth is fuelled by the need
for safe and effective treatment...
Pharmaceutical industry groups today welcomed new government
legislation, which ensures animal extremists who are found guilty
of 'economic damage' to research laboratories will face
imprisonment of five years.
Vitra Bioscience and IDBS have entered into an agreement that
merges IDBS' MathIQ software with Vitra's CellCard System. The
combination of such technologies is an attempt to accelerate the
identification of lead compounds...
Singapore's manufacturing output, which includes pharmaceutical
technology, recorded a 33 per cent growth in 2004, achieving this
target one year ahead of schedule and exceeding projected figures
compiled in 2000.
The latest case of the bird flu passing from human-to-human is
likely to be the first of many after researchers concluded a victim
of the virus may have contracted the disease from her daughter.
A new type of antidepressant drug with a novel mechanism of action,
which acts on a new target, has entered Phase I clinical trials.
The drug could represent a new generation of psycho-active
compounds that are devoid of the problems...
With safety a key issue amongst drug researchers and manufacturers,
Genaissance Pharmaceuticals has expanded its genetic testing
service, which can analyse key cardiac ion channel proteins
involved in drug-induced cardiac arrhythmias.
NMR specialists Bruker Biospin launches the 400 MHz 5mm DCH
CryoProbe, a cryogenically cooled probe that greatly increases
sensitivity and lower detection limits than standard probes.
A new potential diabetes drug from Dia-B Tech, which is based on a
naturally occurring peptide consisting of four amino acids,
promises convenience and fewer side effects over current day
treatments for type 2 diabetes.
Dharmacon and Genentech have entered into a collaboration in which
RNA interference (RNAi) technology is to be used in future drug
discovery and development research. One focus of the deal is gene
silencing, a powerful and increasingly...
Scientists have targeted the alkaloids of the quinolines chemical
family, which have proved effective against visceral leishmaniasis
treating this severe form of the disease with its antiparasitic
properties.
Procognia and Hamilton life sciences have entered into a joint
collaboration, which focuses on the automated growth and handling
of Procognia's functional human protein arrays.
The total global market for Quantum Dots (QD) is expected to exceed
$0.5 billion (€384 million) despite its expense and the novelty of
this technology. The core of this industry drive is expected to
play out in the life sciences and...
Regulatory action on the COX-2 inhibitors was still a possibility
as the European Medicines Agency's Committee for Medicinal Products
for Human Use (CHMP) held hearings with Pfizer, Merck Sharp &
Dohme and Novartis regarding...
Vitra Bioscience has introduced a new nuclear translocation
application, a new method enabling the measurement of
cytoplasm-to-nucleus translocation, a critical indicator of
cellular response to various drug treatments.
US peptide developers Helix BioMedix has entered into collaboration
with Smith & Nephew, which aims to focus on the development of
HB50, the company's lead topical anti-infective peptide.
Allos Theraputics have initiated a phase 1 study of its
investigational drug PDX (pralatrexate) that has so far proved
effective against non-small cell lung cancer (NSCLC). This
treatment has the potential to surpass Methotrexate...
Figures released by the Association of the British Pharmaceutical
Industry (ABPI) has revealed that the level of intimidation posed
by animal extremists reaches as far as the suppliers who do
business with companies involved with...
An emerging trend has identified an emergence of combination drugs,
which could be a solution to patient non-compliance, a major factor
in the rise of drug resistant microorganisms in the industrialised
nations.
The ability of Applied Biosystem's 7500 Fast Real-Time PCR System
to reduce experimental time by almost three times from 2 hours to
approximately 35 minutes, in an industry standard 96-well format,
demonstrates the progress this...
The identification of an oncogene, which is associated with cancers
such as leukaemia, could lead to the development of targeted
molecular therapeutics, controlling cancer development through
regulation of the errant gene.
German biotechnology company MorphoSys' acquisition of two
Biogenesis antibody technology companies elevates it to one of the
largest European suppliers of antibodies to the life sciences
research community.
Pfizer and Rigel Pharmaceuticals have entered into a collaboration
to develop a novel class of compounds for the treatment of allergic
asthma and other respiratory diseases that continue to see cases
rising in Europe and the US.
A new study has revealed the pathway in the learning impairment
caused by liver disease may lead to a drug treatment that would
restore learning ability and provide a viable alternative to
Sildenafil, commonly known as Viagra.
Drug discovery company Cambrex' intention to enter a key segment of
the drug discovery arena was substantiated by its purchase of
immortalised cell lines, related technology and equipment.
Applied Biosystems has launched a polymerase chain reaction (PCR)
system that allows real-time PCR runs to proceed three times
faster. The system's quantitative results are available immediately
without gel runs, purifying PCR...
A new report identifies the nucleic acid (NA) therapeutic market to
reach over $210 billion (€161bn), illustrating a solid and
potentially very profitable approach to treatment of cancer,
rheumatoid arthritis, cardiovascular conditions,...
The pharmaceutical industry took further damage to its reputation
after the Food and Drug Administration (FDA) and healthcare
professionals were warned of the anaemia drug Aranesp, after
studies on similar drugs showed higher doses...
Scientists researching pharmaceutical treatments for Parkinson's
disease are invited to submit study information to a new patient
website, which is intended to improve access to information on
Parkinson's clinical trials,...
German BioMicroscopy supplier ibidi GmbH has launched a range of
"Lab-on-a-Slide" micro-slides (µ-Slides) that can be used for cell
analysis and biomolecules. The slides allow cell culturing and
high-resolution microscopy...
A current trend towards systems biology and analysis and
interactions of proteins and nucleic acids has led Qiagen to
introduce a method that reduces the complexity of proteomics
samples. Currently, researchers use primarily home...
GeneGo has launched an ADME/Tox platform which combines software
for predicting metabolites and over 40 ADME/Tox properties
properties with visualization and analysis of toxicogenomics and
metabolomics data.
Researchers have shed new light on the activation of a protein key
to the development of cancers, particularly breast and prostate
cancer, the most commonly diagnosed cancers in the United States.
Applied Biosystems launches the latest addition to its API family
of triple quadrupole analysers that aims to add to the sensitivity
and accuracy of mass spectrometry for small molecule
quantification, essential for DMPK and ADMET...
The US Food and Drug Administration (FDA) has given clearance to a
new product, which simplifies the process, offers improved
specificity and decreases the time to result in the identification
of methicillin-resistant Staphyloccus...
Scandinavian biopharmaceutical company deCode Genetics intends to
initiate a Phase I clinical trial of the first-in-class treatment
of peripheral arterial occlusive disease (PAOD) which represents a
promising therapeutic approach...