Pharma companies struggling to choose a suitable contract
manufacturer to aseptically produce injectable final drug products
(FDP) may now have the support they need thanks to a new guide
released this week.
A liquidation sale will be held to offload unwanted manufacturing
equipment at a plant formerly owned by Pfizer - much of which is
new and was never turned on or certified.
Lonza has signed two separate deals with California-based Genentech
- a move that illustrates the re-emergence of a relationship
between the two firms.
Valois has made two major instrument investments that will allow it
to dramatically increase productivity as it dons the diving suit to
undertake environmental testing in its cleanrooms.
Wyeth has boosted production at the US plant it has earmarked for
closure while it is dealing with ongoing manufacturing deficiencies
in its Puerto Rico facility.
Asterand is to make available novel research materials to be used
in the investigation of rheumatoid arthritis, osteoarthritis,
cancer and other diseases making available a range of cell material
that is currently difficult to obtain.
DSM Biologics, the biopharma arm of DSM group, has signed a
manufacturing deal with Japanese UMN Pharma based on the firm's
novel recombinant protein manufacturing platform.
Germany's Vetter Pharma-Fertigung has announced its plan to expand
its services by adding vial filling for lyophilised - or
freeze-dried - products to its portfolio.
A new improved range of urethane-based floor systems that is
claimed to help pharma manufacturers reduce the level of bacteria
contamination in their production environment has been launched.
Canadian drug maker LAB International has announced its plan to
acquire Texan PharmaForm in order to speed up the manufacture of
its inhalable anti-pain drug, which will reach late stage clinical
trials next year.
According to the international medical humanitarian organisation
Médecins Sans Frontières (MSF), the World Health Organisation (WHO)
has failed to address the emergence of extensively drug-resistant
(XDR) tuberculosis.
A white paper that looks at the eClinical business model strategies
has concluded that larger investments and access to multicomponent,
single-source contracting options will create more efficient models
for businesses.
The contract packaging biz is moving from an ad-hoc to a more
strategically determined, long-term approach, as pharma companies
begin to relax in the arms of service providers.
A year after it published its five-year strategy: Vision 2010 -
Building on Strengths - DSM's commitment is showing no sign of
slowing as is continues to invest in the expansion of its
pharmaceutical production capabilities around...
US-based drug maker Cleveland BioLabs has teamed up with
biopharmaceutical manufacturer Synco Bio Partners to produce its
leading radioprotection molecule for clinical trials and
commercialisation
The Massachusetts Institute of Technology (MIT) has designed a
portable "lab on a chip" diagnostic device, which the researchers
say could identify biological or chemical weapons faster and easier
than current methods.
Although manufacturing is the most established of the pharma
outsourcing segments, many service areas are still rapidly
evolving. OutsourcingPharma.com gives a brief run down of the
current state of play.
Curalogic, a Danish biotechnology company, has appointed SAFC's
Pharma business segment to provide protein isolation, extraction
and purification services as part of its product development to
treat Allergic Rhinitis.
The Food and Drug Administration (FDA) is expected to issue a
revised version of its regulation on electronic signatures and
records by the end of the year, which will force drug and device
companies to reconsider their current information...
Minimising the risk of cross-contamination in the production of
medicines for use in clinical trials is a major challenge for
manufacturers, who need to implement safety measures in order to
avoid production failure.
Two new drug manufacturing facilities have been launched in global
areas that don't usually see much pharmaceutical manufacturing
activity - Bangladesh and The Gambia.
UK Biopharma company Evolutec has signed a deal with Wacker Biotech
to produce Evolutec's new autoimmune disease drug candidate rEV576
for clinical trials.
Two trade associations of the world's two largest pharma economies
- Europe and the US - took the unusual step of banding together at
the CPhI in Paris to condemn their regulatory authorities for poor
regulation of foreign active...
Using a processing technique described as "revolutionary," DSM is
accelerating its activity in the anti-infective arena and targeting
new active pharmaceutical ingredients (APIs) that it can develop
into cost-competitive...
Arkema has unveiled a new green oxidation catalyst that it claims
"makes environmental protection a priority," as well as
launching a new product website.
Applied Biosystems has announced the availability of the first
laboratory system that uses mass spectrometry to perform amino acid
analysis, greatly improving the effectiveness and reliability of
the data obtained.
Service provider Saltigo is reinforcing its position in the
stabilising fine chemical custom manufacturing industry by
investing in the expansion of its German facility.
Firms engaging in both in-house and contract pharma manufacturing
generally display inferior performance compared to manufacturers
conducting only in-house production, according to new research.
Sigma-Aldrich Group member SAFC made its presence felt at the
recent CPhI in Paris with announcements regarding its expansion
activities in transgenic manufacturing and India.
Pfizer CentreSource has decided to outsource the manufacture of some of its active pharmaceutical ingredients (API) to two Asian contract manufacturers and intends to work with the Food and Drug Administration's (FDA) during the process.
Excelsyn Molecular Development claims to have made a "major
advance" in a protein intensification process that can be used to
slash the manufacturing costs of a range of amino acids.
As it looks to the "future of pharmaceuticals," Sandoz is planning
a "powerful biopharmaceuticals programme" with the construction of
a new biopharmaceuticals development centre in Ljubljana, Slovenia.
In its ambition to become one of the top three global players in
custom manufacturing, the UK subsidiary of drug-maker Nicholas
Piramal (NPIL) has created a new "innovation unit" in Europe.
Filter maker Pall Corporation has announced its plan to invest
about $50m (€63.5m) to expand its life sciences manufacturing
operations in Puerto Rico and take advantage the island's low tax
regime.
Codexis is using India as a springboard to launch it into direct
sales of high-value generic pharmaceutical intermediates, to be
sold into unregulated markets for use in patented drugs.
Rhodia was present at this year's CPhI, alerting the industry to
its latest product updates, spawned out of the market demand to
provide products that allow its customers to better address process
and handling requirements.
Australia's Sigma Pharmaceuticals is attempting to take over the
reigns of smaller domestic rival Australian Pharmaceutical
Industries (API) in a move that if successful, would allow it to
control two thirds of the $9bn Australian...
Raylo Chemical says that it has reduced its manufacturing cycles by
up to 20 per cent and as a result saved hundreds of thousands of
dollars per year after it installed new pH sensing technology.
Agilent Technologies has chosen Distek to be its number-one
provider for dissolution instrumentation service in North America
under its Lab Resource Management (LRM) programme.
Cardinal Health says it is experiencing a "robust market" for its
cell line engineering technology, as it attracts the attention of
pharma giant Wyeth and executes capacity expansion plans its for
full service offerings...
Reaxa has chose the recent CphI to announce it is developing a new
addition to its range of scavenging resins that it claims allows a
huge reduction in product loss in the process of precious metals
clean-up.
Injection molder and contract manufacturer Tech Group is relocating
its Grand Rapids plant to a new molding facility in nearby Walker,
Michigan, which will be expanded to cope with the high demand for
medical devices and components.
In a deal worth up to $19.9m (€15.6m), US drug delivery company
Inyx has acquired contract pharmaceutical packaging firm Pharmapac,
seeking to enhance its secondary-packaging capabilities for a wide
range of dosage forms.
Indian biopharmaceutical company Wockhardt has signed a deal with
Maharashtra Industrial Development Corporation (MIDC) to establish
a special economic zone (SEZ) in Aurangabad, India, in order to
expand its manufacturing capabilities.