Gilead Sciences has announced the initiation of phase I/II clinical
trial evaluating its latest HIV drug treatment that represents a
promising novel class of agents with the potential to inhibit HIV
replication, particularly for patients...
According to a new study, the microscopy sector is set to
capitalise on recent technological breakthroughs, with the
large-scale digitalisation and advances in image reconstruction and
restoration having a positive effect on the market.
New drug treatments and therapies for the management of bowel
cancer is a distinct possibility after researchers made a
surprising discovery about the immune system that details how the
body expels parasitic worms.
In the US, the National Institutes of Health has awarded $88.9
million in grants to nine institutions over three years to
establish a collaborative research network that will use high-tech
screening methods to identify small molecules...
A handful of Alzheimer’s drug treatments and lifestyle-based
interventions shared the spotlight at the first ever Alzheimer’s
Association Prevention conference, in which scientists worldwide
took the opportunity to showcase the latest...
Affymetrix has announced the launch of a scanner, which enables
analysis of microarrays that feature 500 per cent more data than
previous generations making it highly suitable for drug development
applications such as RNA expression...
Researchers have claimed that a fragment of the deadly yellow fever
virus may hold the key to a safer and more effective vaccine,
bringing hope to the 200,000 victims a year. Currently, no drug
treatment is effective against the virus.
Pfizer has struck a deal to buy Vicuron Pharmaceuticals, for $1.9
billion (€1.6 billion) in cash, in a move that places the drug
company further into the realms of anti-infective R&D - an area
thought to be falling out of favour...
The Food and Drug Administration's (FDA) approval of the
first-in-class antibiotic, Tygacil (tigecycline), is set to provide
doctors with an alternative treatment for skin and intra-abdominal
infections that have previously been...
The Global Alliance for TB Drug Development has started testing a
promising tuberculosis drug in humans. This development represents
the first novel compound of a new class to be introduced for the
treatment of TB in more than 40...
The Supreme Court's decision to allow drug companies to receive
exemptions from patent infringement during key early-stage research
carries wider significance throughout the industry as it reduces
licence negotiation for patented...
Kreatech Biotechnology launches a series of array-based labelling
kits for genomic DNA for microarray based comparative genomic
hybridisation analysis, offering a one-step procedure that does not
require the need for amplification.
Teranode Corporation has launched new screening automation software
that claims to be the first ever solution to transform assay design
into assay automation - a tool that is to feature heavily for
screening laboratories with changing...
A US company has revealed a unique method in drug development that
uses transgenic tobacco plants to cultivate the human protein
CaroRx, which could prevent tooth decay in the future.
The European commission came under heavy criticism after rheumatism
was not recognised as a major disease group in its research and
biomedical programme - an outrage, according to The European League
against Rheumatism (EULAR).
The latest research included in the proceedings of the annual
scientific meeting of the American Diabetes Association (ADA) means
that diabetic treatments and other therapies for the disease
feature strongly in DrugResearcher's...
Arena Pharmaceuticals have been issued with a patent for drug
screening methods for the treatment of metabolic-related disorders,
especially in relation to the niacin receptor. Ligands of the
niacin receptor play a role in regulating...
Roche has opened the world's largest polymerase chain reaction
(PCR) manufacturing site in the world, investing more than $150
million and creating approximately 350 new jobs.
Novartis has announced the formation of a collaboration with Anadys
Pharmaceuticals to develop Hepatitis C (HCV) and hepatitis B (HBV)
therapeutics in a deal worth at least $570 million (€466 million).
A new device is set to shorten drug development times by
incorporating a method that details protein structure and
interactions with drugs and medical devices. The device will be
useful for the pharmaceutical industry, particularly...
An opportunity to develop drugs by targeting a recently discovered,
and potentially vulnerable, intermediate stage of the viral life
cycle, could result in a new pharmaceutical treatment in the fight
against HIV and other similar...
Surface Logix has commenced Phase I clinical trials for a novel
PDE-5 inhibitor for the treatment of cardiovascular diseases,
including endothelial dysfunction and erectile dysfunction.
Living Cell Technologies (LCT) are set to put a major dent in the
market for diabetic treatments after they announced the retrieval
of live, insulin-producing cells, from a patient, in a transplant
that did not require the use of...
New anti-breast cancer drugs could be developed after latest
research suggested that Omega-3, a fatty acid found in oily fish,
could be combined with an anaesthetic to reduce the ability of
breast cancer cells to develop into malignant...
Caliper Life Sciences launches a high-volume liquid handling
system, which enables independent control of fluid delivery to
individual microplate wells, becoming only one of a handful of
liquid handlers currently on the market that...
The European pharmaceutical sector is falling behind the US in
terms of innovation and R&D expenditure and is increasingly
under threat from newcomers, especially in India and China.
Dynal Biotech has announced two product releases from its new
proteomic preparation range, which use magnetic bead chromatography
technology to prepare for mass spectrum analysis without the
requirement of columns.
Researchers have identified the first gene in patients who have
epilepsy, which is associated with a movement disorder. The study
provides the first direct genetic evidence that the co-existence of
these conditions represents a new...
Nanostream, has introduced a fraction collector add-on to its
Veloce system, transforming it into a front-end sample preparation
tool that lets users rapidly perform MS assays.
Researchers have come up with a unique method of detecting cancer
in which gold nanoparticles that were bound to a specific antibody
displayed a 600 per cent greater affinity for cancer cells than for
noncancerous cells.
Chiron and the multiple myeloma research consortium have announced
the initiation of a phase I clinical trial for CHIR-258 - the first
drug candidate to undergo clinical study through the MMRC - an
organisation that integrates leading...
Researchers have discovered that a certain virus appears to cloak
itself with a recently discovered gene-silencing device to evade
detection and destruction by immune cells. The study is the first
to show how a virus uses the gene...
Agilent Technologies has introduced the industry's first GC/MS
system that allows researchers to electronically download and share
application methods, accelerating the transfer and method
standardisation across laboratories...
The worldwide market for therapeutic and diagnostic monoclonal
antibodies is expected to reach $26 million (€21.2 million) by
2010, buoyed on by technological advances that allow antibodies to
exhibit a specified targeted attack on...
According to a new report, the US pharmaceutical industry is
ignoring as much as $16 billion (€13 billion) in cash as the
industry struggles to cope with disappointing single-digit growth,
a lack of new products to replace drugs coming...
Bruker Daltonics introduces a novel protein post translational
modification (PTM) discovery tool that represents the first
commercially available Electron Transfer Dissociation (ETD) module
for PTM discovery and de novo peptide sequencing...
Affymetrix has signed an agreement to acquire ParAllele Bioscience
- a move intended to broaden its variety of microarray
applications. This acquisition builds on a two-year collaboration
between the two companies.
Targepeutics has announced the issuance of a patent that targets
brain cancer compounds, specifically used to treat malignant
glioma. The more specific targeting should allow broader and safer
application of recombinant cytotoxins.
Qiagen has acquired the PCR diagnostics company Artus, in a move
that now allows Qiagen to offer preanalytical sample preparation
and diagnostic assay solutions to its partners in molecular
diagnostics. The acquisition further allows...
Pfizer has entered a worldwide collaboration and licensing
agreement with Renovis to research, develop and commercialise small
molecules that target a receptor, which generates signals for
certain types of pain.
An official of the Food and Drug Administration (FDA) has admitted
that the regulatory agency was "the single greatest obstacle to
doing anything effective" regarding Vioxx, adding that the FDA
could have prevented the...
According to data presented this week, multiple second-generation
antisense drugs that show potential as new treatments for asthma
could represent the future in treating this disorder that has
soared in worldwide cases, particularly...
Chemical Abstracts Service and FIZ Karlsruhe have launched new
software that is set to provide insights into trends and patterns
in scientific and patent information, which is achievable through
greater value from search results.
US researchers have identified an enzyme activity that is
inactivated in all reported mutant forms of a disease protein,
opening up opportunities for therapies to treat ataxia, a rare
hereditary neurological disease that affects 1/100,000...
Targeted Genetics Corporation announced the issuance of a new
patent, which covers the company's approach to increase carrying
capacity of adeno-associated virus (AAV) technology platform
expanding the potential applications...
Ablynx has announced that it had signed a collaborative agreement
with the National Research Council of Canada (NRC) Institute for
Biological Sciences (IBS) that aims to concentrate its discovery
efforts in the area of neurodegenerative...
NanoLogix unveils its DNA extraction system for the molecular
diagnostics market, which is said to take significantly less time
than standard spin column extraction methods.
According to a recent report, the global bioinformatics market is
currently estimated at about $1.4 billion (€1.1 billion). It is
expected to grow at an average annual growth rate of 15.8 per cent
to reach nearly $3 billion by 2010,...
Novartis'collaboration with Myogen looks to have been a shrewd move
as Myogen report the extension to the original agreement to include
its histone deacetylase inhibitor (HDACi) program. In addition,
Myogen has achieved three...