Genomic Solutions launches proprietary technology that automates
and minitaturises protein crystallisation screening, dispensing
both precipitant/mother liquors and protein in volumes ranging from
100 nanolitres to 100 microlitres.
A two-year study has recommended a greater focus in looking for
other methods of conducting medical research, as the continued use
of animals in experiments is both unrealistic and ethically
controversial.
Merck KGaA announced its intention to relocate its pharmaceutical
research operations in Scotland to its larger biotech research
facility in the United States, withdrawing its DeImmunisation
technology service at the same time.
BioInvent become the latest company to enter the HIV/AIDS drug
arena after UK authorities gave the go ahead to commence the
company's first clinical trial of its human antibody to treat the
virus.
Qiagen has released two protein purification kits that provide
affordable automation as a way to increase throughput and free up
valuable manpower for less routine tasks.
Editors of eleven international medical journals have amplified
their call for the registration of drug trials before the first
patient is enrolled,in a medium that is fully searchable and
publicly accessible at no charge.
GlaxoSmithKline (GSK) has created a Centre of Excellence for
External Drug Discovery (CEEDD) that aims to provide GSK with
alternative scientific and drug discovery approaches. The CEEDD
also aims to exploit the full potential of...
Biotechnology company, Biogen has announced the identification of a
molecule that may play a key role in the repair and regeneration of
the central nervous system (CNS). The finding could lead to
potential pathways for treating multiple...
According to a new survey, there are currently 399 new medicines in
development now to treat cancer. The survey shows that many of
these medicines represent potential breakthrough cancer treatments,
while others involve possible new...
Scientists have reported that a molecule previously thought to play
a purely structural and inert role in cells may play a key role in
bringing about multidrug resistance in cancer.
US researchers have developed the first animal model that clearly
defines cancer metastasises in all the same places that human
pancreatic cancer spreads to such as the liver, lungs, diaphragm,
and adrenal glands.
According to a new report the struggle to meet the escalating
health problem of an increasingly ageing population is being
replaced by a focus on treatment that prevents or delays the onset
of disease, personalising medicine to each...
A new understanding of specialised gut hormones may lead to
advances in the treatment and management of type 2 diabetes,
offering patients a viable option in controlling fluctuating blood
glucose levels that is characteristic of the...
Biotechnology company, Affitech, has entered into a collaboration
agreement for two promising new cancer-specific human antibodies
using its Cell-Based Antibody Selection technology (CBAS).
In the wake of the latest American Society of Clinical Oncology's
(ASCO) annual conference, drug companies from around the world
showcased potential drug treatments, with a number of new molecular
targets as well as therapy strategies...
MedImmune has announced Phase I clinical trial results of an
antibody that appeared to be safe and well tolerated in patients
with certain T-cell lymphomas and leukemias. The results signify
the emergence of monoclonal antibodies...
Qiagen and Procognia have entered into a marketing and licensing
agreement, which targets the emerging field of protein
glycoanalysis. The combination of Qproteome products with
Procognia's On-Chip Glycoanalysis technology aims...
Biotechnology company, ArQule, have reported evidence of
anti-tumour activity of its drug candidate that has a mechanism of
action based on its Activated Checkpoint Therapy (ACT) platform and
represents the latest monotherapeutic...
Osteoporosis, which has developed into a multibillion-dollar
market, and is dominated by Merck's Fosamax and Proctor &
Gamble/Sanofi-Aventis' Actonel, now faces new competition after the
Food and Drug Administration...
A former editor of the British Medical Journal (BMJ) claims that
medical journals are an extension of the marketing arm of
pharmaceutical companies, placing editors in difficult positions as
company-funded trials are becoming increasingly...
According to a latest study, which revealed the presence of a
unique genetic biomarker, the quality of life for patients
undergoing treatment for colorectal cancer may be significantly
improved, potentially minimising the unwanted...
According to a new report, Applied Biosystems/MDS Sciex is the
leading mass spectrometer brand in all regions and market segments.
Suppliers in this market will benefit from the 19 per cent of mass
spectrometer users surveyed who...
Genevac has introduced new technology for its Model HT-4X
centrifugal evaporator whereby the system can be used to accelerate
lyophilisation of water and water mixtures by as much as three
hundred per cent.
Qiagen and Epigenomics have entered into a collaboration to jointly
develop and introduce preanalytical solutions for DNA methylation
analysis to focus on in-vitro diagnosis (IVD) and pharmacogenomics
markets.
Intermune has announced the results of preclinical data on the
specificity and tolerability of two potent and selective small
molecule inhibitors of the hepatitis C virus (HCV). The findings
are significant, as they have previously...
Eksigent Technologies introduces a new range of software drivers
and hardware accessories that ensure sample delivery at a pace that
improves the throughput of its eight-channel HPLC system.
Researchers may have found a novel way to fight asthma by targeting
a protein that is centrally involved in the bronchial inflammation
and airway constriction that prompts asthma's hallmark symptoms.
The antibody treatment is...
Biosample management firm, GenVault announced an exclusive
agreement to acquire the full rights to a DNA labelling
intellectual property, which allows researchers to identify the
sample through its complete downstream analysis to...
According to a new report by the National Academies, the advent of
increased global competition for outstanding students and
scientists has heightened the need for a widespread effort to
attract high calibre researchers to the US.
Biopharmaceutical company, Cytogen, and contract services provider
Dowpharma have announced a collaboration to create a targeted
oncology product designed to treat prostate and other cancers. The
new treatment also demonstrates the...
According to a new report the therapeutic antibody market is
expected to treble in size by 2010 as significant leaps forward
coupled with safer and more effective humanised and fully human
antibodies are pouring onto the market fulfilling...
Medarex has announced the initiation of a phase I clinical trial of
its human monoclonal antibody for the treatment of ulcerative
colitis after the FDA granted the company an Investigational New
Drug (IND) application.
Vertex Pharmaceuticals have announced the latest results that
indicate the investigational oral hepatitis C virus (HCV) protease
inhibitor VX-950 was well tolerated and demonstrated potent
antiviral activity in a Phase Ib clinical...
Wyatt Technology is set to offer its first integrated solution for
batch dynamic light scattering, which are amongst a batch of
products set to bring improved high throughput screening and better
understanding of the physical attributes...
Sangamo BioSciences has initiated a Phase I clinical trial for its
novel therapy for diabetic neuropathy that is designed to protect
and stimulate the regeneration of peripheral nerve function in
diabetics suffering from peripheral...
US researchers think they have found promising new molecular
targets and treatment approaches for malignant brain tumours,
suggesting a new therapy for anti-cancer drugs.
A new laboratory technique used by fruit fly geneticists for more
than a decade is now available to scientists studying genes and
diseases in mice. This technique offers a powerful new tool to
study genetics, particularly in disease.
A patent has been issued to Arena Pharmaceuticals for its small
molecule treatment for obesity, which targets a specific receptor,
thought to be involved in the regulation of food intake and may be
useful in pharmaceutical compositions...
Arrayjet launches a new inkjet microarray spotter, which uses a
modern, replaceable inkjet print head with over 100 nozzles to
deliver samples to the array surface. The non-contact technology
also has a unique replaceable inject print...
Bio-Tek Instruments and LI-COR Biosciences announce the integration
of Bio-Tek's Bio-Stack Microplate Stacker to LI-COR's new Aerius
Automated Infrared Imaging System, a microplate reader providing
automated data analysis...
Eyetech Pharmaceuticals' latest study has demonstrated the
significance of VEGF164 in pathological neovascularisation,
providing further evidence of the therapeutic benefits of a VEGF
inhibitor that specifically targets an underlying...
VIRxSYS has announced the completion of the phase I study of its
novel HIV gene therapy, which has been touted as the first of a
next-generation anti-HIV treatment involving gene therapy. The
positive results mean a phase II study...
Qiagen has announced the acquisition of RNAture's nucleic acid
isolation products from Hitachi Chemical Research Centre. The
latest acquisition sees Qiagen purchase an extensive range of
products that addresses high-throughput...
GlaxoSmithKline has announced plans to acquire the Corixa
Corporation, which represents an important strategic deal for GSK's
vaccines division, GSK Bio. The division is the only major vaccine
maker with active R&D programs...
Celera Genomics have filed an Investigational New Drug (IND)
application for a novel histone deacetylase (HDAC) inhibitor that
has proved effective in inhibiting cancer cell proliferation. The
filing also signifies Celera's transformation...
Waters Corporation has launched the MassTrak Clinical Solutions, a
system that is aimed at monitoring and measuring drug therapies,
performing toxicology screening and quantifying biomarkers quickly,
reliably and accurately.
Researchers in the US have found that blocking the COX-1, not COX-2
enzyme, might lead the way to prevent and treat the most common and
fatal form of ovarian cancer.
A worldwide agreement to develop and commercialise a fully human
monoclonal antibody that could have therapeutic potential in the
treatment of T-cell mediated diseases has been agreed between
Serono and Genmab.
Isis Pharmaceuticals is developing its first inhaled antisense drug
for the treatment of asthma and related pulmonary diseases. The
drug represents a potentially effective therapy for these diseases
that continue to see cases rising...