Researchers claim to have developed a drug delivery system capable of passing through the mucus barrier, which had previously been impenetrable to therapeutics.
OIMBL’s PharmaSense is a versatile MRI tool that allows drugmakers to assess tablet dynamics and potentially improve API delivery, according to company managing director Frank Trundle.
US-based biotech ArmaGen Technologies has received funding from the Michael J Fox Foundation (MJFF) for the development of its drug delivery technology.
US researchers have developed a chemoenzymatic strategy to synthesise the anticoagulant drug heparin and avoid the contaminant that has killed more than 80 people.
CRO Rubicon Research and chemicals manufacturer Mallinckrodt Baker are teaming up to develop the PanExcea excipient range, which was launched by the latter firm’s parent company Covidien in July.
Conformia says that the integration of its SOA data platform into IBM’s system will provide drugmakers with robust management architecture for the entire lifecycle of a product.
US-based DSM Biologics and MorphoSys are teaming up to manufacture the MOR202 antibody, which has shown considerable promise as a treatment for multiple myeloma (MM).
The gulf in rates of growth between emerging and established markets in the biotech active pharmaceutical ingredient (API) sector has been highlighted in a new report from the Chemical Pharmaceutical Generic Association (CPA).
US R&D organisation Draper Laboratory has unveiled plans to set up a new centre to develop and produce of its bioMEMS technology for therapeutic and healthcare applications.
in-PharmaTechnologist’s periodic round up of developments in the field of drug delivery includes BioDelivery initiating Phase I studies, success for Titan and a novel use for Viagra.
FDA officials have impounded nearly $24m (€15.4m) worth of guaifenesin-containing timed-release (TR) cough and cold medicines made by US specialty drugmaker KV Pharmaceuticals.
Brookwood Pharmaceuticals, a subsidiary of SurModics, has acquired the exclusive rights to all pharmaceutical applications of PharmaSol’s nanostructured lipid carrier (NLC) technology.
A new excipient could help drugmakers improve the delivery profiles
of active pharmaceutical ingredients (API), according to US
developer Eastman Chemical.
Modigene says that data from a trial of a Schering-Plough's (SP)
fertility stimulation hormone (FSH-CTP) confirms that carboxyl
terminal peptide (CTP) modification can extend the therapeutic
duration of protein drugs.
Sangamo Biosciences and Sigma-Aldrich have licensed their zinc
finger nuclease (ZFN) technology to Roche to enable the pharma
giant to develop cell lines and transgenic animals.
Praxair China has won the contract to supply the liquid nitrogen
and cooling system for Jiangsu Defeng Pharmaceutical &
Chemical's manufacturing plant.
A new Master Cell Bank (MCB) capable of producing pure cell culture
for the manufacture of the anti-biofilm enzyme DispersinB
represents a significant breakthrough, according to developer Kane
Biotech.
A deal to sell Pfizer's active pharmaceutical ingredient manufacturing (API) plant in County Cork, Ireland, has fallen through according to a statement by the US drug giant, placing over 180 production jobs under threat.
Vivalis has filed the biologics master file (BMF) with the US Food
and Drug Administration for its EB66 vaccine and therapeutic
protein production technology.
Slovenian drugmaker Krka has paid just under $1.6m (€1m) for 7.5
per cent stakes in two Chinese drug and chemicals firms, namely
Zhejiang Menovo Pharmaceuticals and Anhui Menovo Pharmaceuticals.
Nventa Biopharmaceuticals hopes that the enhanced durability of its
new Poly IC-Poly arginine (Poly-ICR) adjuvant will help it capture
a significant share of the therapeutic and prophylactic vaccine
markets.
The PER.C6 cell culture-based antibody production platform has
achieved a new record yield of 27 grams of IgG antibody per litre,
bettering the 15 gram per litre mark that was reported earlier in
the year.
Germany's Bayer hopes that its pilot-scale production facility in
Halle, Saxony-Anhalt will help establish its tobacco plant-based
expression system as leader of the lucrative protein manufacturing
sector.
Baxter has successfully produced H5N1 influenza vaccine in African
green monkey kidney cells in quantities sufficient for clinical
testing, according to an article published in The New England
Journal of Medicine.
Japanese glass and chemical company Central Glass has found a swift
route into the contract manufacturing market for active
pharmaceutical ingredients (APIs) in Europe via the purchase of
Girindus' facility in Halle-Kuensebeck.
Contract pharmaceutical services supplier Arch Pharmalabs has
purchased a 70 per cent stake in fellow India-based active
pharmaceutical supplier (API) Benzochem Lifesciences for around Rs
1bn ($23m), strengthening its position in...
Contract manufacturing group Helix Medical hopes that expansion of
its global production capacity will help it corner the
pharmaceutical industry's injection moulding thermoplastics market.
Genetically modified (GM) maize is the most effective
biomanufacturing platform for the production of monoclonal
antibodies to combat HIV, according to research published in
PNAS.
An artificial self-assembling virus capable of serving as a drug
delivery system has been created by researchers in Korea, according
to a publication in Angewandte Chemie.
Buccal drug delivery specialist Generex Biotechnology reports that
the production of its chewing gum-based metformin, MetControl, has
been completed ahead of forthcoming trials in patients with
diabetes.
Archimedes Development, a subsidiary of Archimedes Pharma, expects
that the intellectual property it has licensed from fellow UK firm
Ploughshare Innovations will help extend the application of its
ChiSys drug delivery system.
Switzerland-based Schweizerhall appears to have circumnavigated
patent law, with approval of its generic version of Bristol-Myers
Squibb's (BSM) and Sanofi-Aventis' Plavix (clopidogrel bisulfate)
in Germany "expected...
China is on course to having its own version of the International
Pharmaceutical Excipients Council - joining its fellow
organisations in Europe, the Americas and Japan.
Teva's sales of active pharmaceutical ingredients (APIs) for the
first quarter of 2008 rose by 51 per cent on the previous years
figure, taking to total to $510m.
UK-based AM Technology has developed the Coflore Agitated Cell
Reactor (ACR) which it claims offers significant advantages over
traditional continuous stirred tank reactors.
US drugmaker Unigene has begun construction of new facilities in
China as part of its joint venture with a state-owned Chinese
pharmaceutical company to establish research, development and
manufacturing capacities in the nation.
Germany-based Gene Bridges has licensed its Red/ET Recombineering
technology to Novozymes for genetically engineering recombinant
micro-organisms for use in industrial applications.
