GEA Pharma Systems' Collette unit will present Consigma, its new
continuous high shear granulation and drying system, at the
Interpack exhibition in Düsseldorf later this month.
Eli Lilly plans to cut 500 jobs, mainly in manufacturing, as it
attempts to restructure its operations to mitigate against the
losses from inhaled insulin.
The US Food and Drug Administration (FDA) believes that the
contamination of Baxter's blood thinner heparin, which has been
linked to 62 deaths in the US, may have been due to the deliberate
replacement of some ingredients with...
The number of people whose deaths are associated with an allergic
reaction to heparin has shot up as the US Food and Drug
Administration (FDA) has updated its tally.
GlaxoSmithKline has opted not to sign an exclusive development
agreement with UK sexual health specialist Futura Health for its
transdermal pain relief product, TPR100.
US-based Delcath Systems has achieved positive results in treating
diffuse liver cancer using its percutaneous hepatic perfusion (PHP)
delivery system.
The pharmacopoeias of the US and China will work more closely
together in future in a bid to improve the quality of medicines
available in both countries.
Denmark's Novozymes has signed an exclusive worldwide licensing
agreement with CSL Behring for albufuse, a proprietary albumin
fusion technology that can extend the circulatory half-life of
therapeutic proteins through genetic...
A planned $60-$70m (€38-€44m) initial public offering (IPO) by
US-based drug delivery specialist MonoSol Rx has fallen foul of the
credit crunch and fears about a slowing US economy.
IntelliPharmaCeutics is ready to move into full-scale clinical
trials with a once-daily oral formulation of oxycodone based on the
company's ReXista abuse- and alcohol-resistant technology.
Canada's SemBioSys Genetics has begun final pre-clinical studies of
its novel plant-produced insulin product in preparation for its
submission to US regulatory authorities.
They showed promise in everything from drug delivery to the
development of superconductive compounds, but so far fullerenes
have been difficult to produce and purify in sufficiently large
quantities for useful applications.
Cambrex Corp, the US-based manufacturer of small-molecule active
pharmaceutical ingredients (APIs) and advanced intermediates for
the drug industry, has announced that one of its customers is
recalling a product for which Cambrex...
Switzerland's Siegfried Holding says that a significant jump in
2007 net profit, up 54 per cent to CHF 49.7m ($50m), vindicates its
decision to refocus on the active pharmaceutical ingredients and
generics sector.
A revised glycerin monograph has been announced at the US
Pharmacopeial (USP) Convention which it is hoped will further
decrease the likelihood of health hazards associated with
diethylene glycol-contaminated glycerin.
The costs of introducing any formal good manufacturing practice
(GMP) requirements for potentially high-risk pharmaceutical
excipients in the European Union would far exceed the likely
benefits, concludes an impact assessment for...
Drug delivery specialist Eurand could see a marked increase in
revenue flow this year, both from co-development products
incorporating the company's formulation technologies and a
proprietary treatment addressing the estimated...
The CEO of Californian company Nektar Therapeutics says that 2007
has been key in transforming the company into a fully integrated
drug development organisation, despite the setback with Pfizer's
inhaled insulin product Exubera.
The prospects for a viable market in inhaled insulin therapies were
looking markedly thinner this week after Eli Lilly pulled the plug
on its joint development programme with drug delivery specialist
Alkermes for AIR Insulin.
Flamel Technologies has yet again experienced a net loss of $37.2m
for 2007, following a string of bad fortune in 2005 and 2006, but
believes it may be about to turn the corner.
Scientists have provoked a soil-dwelling bacteria into producing a
potent antibiotic by pitting it against another bacteria, despite
the fact that previously it had never been known to produce such
products.
German chemicals giant BASF has announced its latest brace of price
rises, this time for two forms of carboxylic acid and for bleaching
and reducing agents.
With active pharmaceutical ingredient sales of $1,460m (€960.8m) in
2007 and a portfolio of more than 250 compounds, Teva
Pharmaceutical Industries is by a long stretch the dominant
supplier in the global API market.
A long-acting injectable formulation of Eli Lilly's blockbuster
schizophrenia treatment Zyprexa (olanzapine), with the potential to
improve patient adherence and take some of the sting out of generic
competition three years down...
UK specialty pharmaceutical company Glide Pharma has signed a deal
with a "leading" pharmaceutical company, under which the as yet
unidentified firm will evaluate Glide's Solid Dose Injection system
for the administration...
Jubilant Organosys, India's largest custom research and
manufacturing services (CRAMS) provider, has scored new contracts
to the tune of $92m for the year thus far as its business continues
to gather momentum.
Accu-Break Pharmaceuticals (ABP), the US company with a suite of
tableting technologies for creating divisible dosage forms, has
signed a co-operation agreement with Germany's Midas Pharma that
should open new avenues for technology...
Denmark's Novozymes has renewed and extended its collaboration with
UK-based biotech Upperton Limited on a drug delivery system that
exploits the natural binding properties of recombinant protein
nanoparticles to improve compound...
A new recombinant pig liver esterase (PLE) biocatalyst that
sidesteps concerns about the safety of animal-derived versions has
been launched by DSM Pharma Chemicals.
A nanoparticle-based delivery system is being developed in the UK
as a potential means of bypassing the blood brain barrier and
improve the treatment of central nervous system diseases such as
brain cancer.
A novel delivery system that converts the structure of cartilage
"from a barrier into a reservoir" could provide an answer
to the challenge of administering and maintaining drugs in
avascular tissue.
The first European approval application for a vaccine delivered via
a new intradermal (ID) microinjection system developed by BD
(Becton, Dickinson & Company) has been filed by Sanofi-Pasteur,
the vaccines division of the Sanofi-Aventis...
A Phase II clinical trial using French company
Polyplus-transfection's innovative gene delivery tool, in
vivo-jetPEI, is set to go ahead this month in Europe and the
US.
UK drug delivery specialist SkyePharma has signed an agreement with
India's Dr Reddy's Laboratories for a feasibility study of an
unnamed product using two of SkyePharma's proprietary drug delivery
systems.
A new study has demonstrated for the first that microneedle
technology is able to overcome some of the barriers preventing the
transdermal administration of drugs with low bioavailability.
The green tea polyphenol (-)-epicatechin-3-gallate (ECG) may slash
the risk of gastric cancer among women by 75 per cent, suggests a
new study from Japan.
Alpharma has signed a definitive agreement with private equity
group 3i for the sale of its active pharmaceutical ingredient (API)
business, pocketing $395m in the deal to reinvest in its
pharmaceutical and animal health divisions.
The Spanish subsidiary of UK-based biological nanoparticles
specialist Midatech Group has signed a licence agreement giving it
new leeway to exploit the therapeutic potential of noble metal
nanoparticles.
US biotech Neose Technologies has dropped its lead compound,
NE-180, a PEGylated form of erythropoietin, from development,
saying concerns over the safety of erythropoiesis-stimulating
agents (ESAs) have blunted not only the drug's...
Merck & Co has expanded its licensing agreement with SurModics
in a further endorsement of the latter's I-vation drug delivery
system for eye diseases.
In the world of chemistry the majority of reactions are well known
and have been around for a very long time producing similar
compounds. It is not very often that a completely new reaction
methodology comes along which can turn something...
MiddleBrook Pharmaceuticals secured a crucial endorsement for its
Pulsys oral drug delivery system last week when the US Food and
Drug Administration (FDA) approved the company's lead pipeline
product, Moxatag, as a once-daily...
With the price of crude oil going up almost every day it is no
surprise that this has a knock-on effect to the price of raw
materials for the pharmaceutical and chemical industries. But DSM
and Roquette have developed a process that...
Novartis has announced the US approval of its first-in-class blood
pressure med Tekturna (aliskiren) combined with a diuretic in a
single-tablet formulation.