Emisphere Technologies has demonstrated effective oral delivery of
protein-based drugs in three studies presented at the Controlled
Release Society's annual meeting.
LipoCore's Galacticle delivery technology is to be the subject of a
feasibility study at one of the largest multinational drug
manufacturers in the autumn
A deal with Vaccinex has taken Lonza Biologics beyond its primary
focus of mammalian cell culture-based manufacturing and into the
area of antibody drug discovery.
The shift towards full automation with ready-to-use separation
devices is the first step on the path to a completely disposable
manufacturing process, says Millipore
Ultrasound monitoring of process column chromatography can lead to
significant improvements in productivity, lower costs and greater
drug purity, says study
GlaxoSmithKline has opened an ultra-high-throughput screening
facility at its site in Tres Cantos, Spain, marking a significant
milestone in the company's bid to develop a more industrialised
approach to the process of drug discovery.
Centocor forged a deal with Biolex in which the latter firm will
examine the feasibility of producing three therapeutic proteins
using a proprietary plant-based expression system
MediGene is relocating the entire research department of its US
subsidiary to Germany, delighting those who lament the "brain
drain" of scientific talent flowing in the other direction
There has been a steady increase in the number of diabetes-related
R&D projects in recent years, and one area of particular
interest is the pulmonary delivery of insulin, says a new report
Switzerland's Novartis has been awarded a US patent for a novel
means of extending the shelf life of pharmaceuticals. The invention
describes the use of a plastic bottle made from a polymeric
material that is impregnated with...
Researchers in the USA have generated designer metal oxides with
specific surface properties that can be used as catalysts in the
manufacture of pharmaceuticals and chemicals
Avantium Technologies of the Netherlands, a specialist in
developing high throughput process R&D techniques for customers
in the chemical and pharmaceutical industries, has been signed up
by Eastman Chemical for the discovery...
Bruker Daltonics has forged an alliance with the US Pacific
Northwest National Laboratory to develop and commercialise mass
spectrometry for high-throughput proteomics research
Nature Technology has launched an improved delivery technology for
DNA vaccines that is now available for license by companies working
in this fast-growing area
Transgenomic has taken out a non-exclusive licence from Geron in
which it gains manufacturing rights to phosphoramidate and
thio-phosphoramidate oligonucleotides.
Boston Biomedica has been issued an additional US patent covering
the design and use of its Pressure Cycling Technology for the
control of pressure-sensitive chemical reactions.
METabolic EXplorer, a French biotechnology company specialising in
the development and production of new biological processes for the
manufacturing of chemicals and pharmaceuticals, has bolstered its
scientific team with the appointment...
AstraZeneca has opened a new multi-million dollar research facility
in Bangalore, India, which will focus principally on finding new
treatments for tuberculosis, a disease which is diagnosed in about
8 million people worldwide each...
Germany-based drugmaker Merck KGaA has launched a major
restructuring of its R&D activities after shelving two of its
early-stage diabetes product candidates, EML 16336 and IDD 676.
A science and technology advisory group has called on the Irish
government to ensure that the country remains competitive in the
pharmaceutical and chemical industries by developing R&D
operations and, in particular, fostering...
Reports in Ireland have suggested that Germany's Schwarz Pharma is
planning to scale back its operations in Shannon and cut its
workforce. The company is allegedly planning to reduce its Irish
workforce by 70 to around 180 staff.
US biopharmaceutical firm Acceptys has licensed an immortal
humanised cell line from Columbia University, which will allow it
to discover and produce fully human monoclonal antibodies and other
human proteins for use as therapeutic...
Belgian pharmaceutical and chemicals firm Solvay expects to launch
a new version of its Influvac brand flu vaccine, based on a novel
cell-based production process, in 2005. The speed of the new
process means that a vaccine can be...
Sweden's Amarin Development has been commissioned by GEA
Farmaceutisk Fabrik, a Danish subsidiary of German pharmaceutical
company HEXAL, to develop a formulation of one of its candidate
compounds.
BASF AG's Fine Chemicals division is expanding production of
pharmaceutical active ingredients with the construction of a new
plant at its site in Minden, Germany. A spokesman for the company
told In-pharmatechnologist.com that...
New bulk drug manufacturing facilities, worth a total of around
€123 million (£90 million), were officially opened this week at
AstraZeneca's Avlon Works near Bristol in the UK.
An international conference serving global centres of excellence
for biotechnology, so-called 'bio-technopoles,' life science parks
and 'bio-incubators' will take place ahead of the 7th European
Biotech Crossroads...
BASF Plant Science, the plant biotechnology subsidiary of chemical
giant BASF, has entered into an agreement with Cellectis,
specialists in genome engineering and a recent spin-off from the
Institut Pasteur, that will provide BASF...
An EU funded project is building the critical mass of knowledge
required to ensure that Europe meets the Lisbon objective of
becoming the world's most competitive knowledge-based economy by
2010, reports Cordis.
Strasbourg, France-based Aventis has signed a research, option and
license agreement with Vivalis of the USA for the manufacture of
vaccine candidates using avian stem cell technology.
The European Commission has proposed new regulations allowing
Member States to grant aid for research and development (R&D)
to small and medium sized enterprises (SMEs), without having to
first apply for clearance from the Commission,...
Architects of the new instruments for the Sixth Framework Programme
will be heartened by news that a German report on the country's
networks of competence has concluded that such arrangements
stimulate innovation and, in turn,...
Research into genomes of the natural world took a step forward this
week with the announcement from Diversa corporation that it is to
jointly collaborate with the US Department of Energy's Joint Genome
Institute (JGI) to discover...
In a bid to increase European competitity in the global research
arena the European Commission announced new measures destined to
encourage public and private players across Europe to upgrade their
research effort.
The Netherlands-based organisation for Applied Scientific Research
(TNO) has signed an agreement with GlaxoSmithKline to collaborate
in the development and use of TNO's in vitro models of the
human gastrointestinal (or "GI")...
Ireland is developing a sound research base in the areas of
biotechnology and information and communication technologies (ICT),
despite institutional and funding barriers, concludes a recent
report by the national policy and advisory...
Prominent US genomics Robert L. Strausberg, who directs the
National Cancer Institute's (NCI) Cancer Genomics office, has been
named as vice president for research at The Institute for Genomic
Research (TIGR).
Engineers in the US are one step closer to mass-producing
therapeutic proteins needed by today's pharmaceutical industry.
Researchers claim to have achieved a major milestone in their
efforts to effectively produce human therapeutics...
The biotechnology industry in the state of British Columbia in
Canada could double the number of companies, attract large
revenue-generating biotechnology firms and create more than 5,000
new jobs within five years, says a strategic...
A prominent US law professor from Stanford University has called
for an international treaty on sharing scientific and technological
information, to be based on the arrangements already agreed for
free trade under the World Trade...
Billion dollar science and technology company Dowpharma, a business
unit of The Dow Chemical company, has announced new capabilities in
catalytic asymmetric hydroformylation (AHF) of olefins for
applications in the development and...
Akzo Nobel business unit Diosynth, which specialises in the
production of complex active biopharmaceutical ingredients for the
pharmaceutical sector, has developed a new method for manufacturing
synthetic peptides that, it claims,...
An expert group on intellectual property rights (IPRs) has warned
that rules governing the protection of copyrights, database rights
and patents hamper scientific endeavour and must be changed 'in the
interest of society',...
Researchers have now completed the sequencing of the human genome,
to an accuracy of 99.999 per cent, nearly three years after the
first 'working' draft was published to great fanfare in June 2000.
The achievement comes...
The European Commission has earmarked €13 million from the budget
of the EU's Sixth Research Framework Programme (FP6) (2002-2006) to
promote and facilitate research co-operation with the 13 associated
candidate countries for...
As the lead story today on In-Pharmatechnologist.com
highlights, the European brain-drain is far from slowing down with
the US continuing to attract researchers and entrepreneurs. A fact
that has had, and will continue to have, a...
Until recently nanotechnologists -- scientists who build devices
and materials one atom or molecule at a time -- concentrated almost
entirely on electronics, computers, telecommunications, and
materials manufacture. Now biomedical...