A new study holds much promise for a new approach to drug therapy
after researchers have revealed details of a mechanism that
actually modifies the effect of a major drug class.
PPD has announced it has signed an agreement with PDL BioPharma in
which the contract research organisation is to perform
comprehensive molecular profiling to discover biomarkers.
Greiner Bio-One presents its cell culture AutoFlask at the
Analytica show, which uses a robot accessible entry septum that
prevents coring by pipette tips and ensures sterility of the flask
contents throughout solution exchanges.
Bruker BioSpin has launched the world's highest field actively
shielded NMR magnet at 950 MHz, which allows higher sensitivity and
unrivalled spectral dispersion whilst maintaining same size
cryostat and identical cryogenic performance...
Perbio Science took the opportunity to provide a company update at
this year's Analytica show in Munich with details of new product
launches for drug discovery.
Ilypsa has completed the first stage of its novel phosphate-binding
agent designed to treat hyperphosphatemia, as the company plough
forward with its pioneering research into next-generation
nonabsorbed polymeric drugs for renal and...
China-based Natural Pharmatech has formed its first research
contract with a Japanese company, Kobayashi Pharmaceutical -
another step forward in Natural Pharmatech's plans to bring its
botanical R&D services to the global...
Chronic diseases account for 70 per cent of the healthcare budget
in the UK alone. New drugs in unment chronic disease areas offer
real blockbuster potential for companies willing to take on the
challenge.
The US Navy has extended an existing deal with Austrian biotech
company CEL-SCI to further investigate the company's novel drug
compound, CEL-1000, that could offer 100 per cent protection
against Malaria.
Polymer Laboratories have launched a new Evaporative Light
Scattering Detector (ELSD) that it claims will improve the analysis
of pharmaceutical compounds at low temperatures.
A target-seeking molecule that can be used to visualise and treat
cancer tumours is set to improve detection and treatment of the
killer disease, which is a lot more successful if therapy begins at
an earlier stage.
Scientists think that their latest discovery could result in the
production of new drugs to treat Kaposi sarcoma tumour growth,
which is the most frequent tumour in AIDS patients and is caused by
infection of the patients with the...
An AstraZeneca collaboration has identified the location of a
schizophrenia gene that is set to offer hope for more effective
drugs. The gene appears to affect the production of myelin, the
material that insulates nerve fibres.
Discovery Partners International is offloading its unprofitable
contract drug discovery operations and merging with Infinity
Pharmaceuticals to create a new public company focused on cancer
drug discovery and development.
A pioneering website has been set up that enables members of the UK
public to express their support for medical research that uses
animals as subjects.
Researchers think they have found a gene, which when disrupted
interferes with the ability to absorb lipids through the intestine.
The discovery has added to new insights into mechanisms behind
lipid and cholesterol processing, and...
Bertin Technologies makes available its solution for biological
sample preparation to extract nucleic acids (DNA & RNA), and
proteins - a crucial process in drug discovery and development as
well as having implications in the...
ESA Biosciences make available its HPLC detection tool that is
designed for laboratories that use THF (tetrahydrofuran) as a
component in chromatographic separations and sample analyses.
A new interactive voice response (IVR) package is available for
small clinical trials, aimed at companies who previously found this
technology unaffordable.
A team of researchers have developed a strategy in which genes
linked to cancer mutations could easily be identified aiding
predictions as to which patient will respond favourably to novel
drug treatments.
Despite lingering ethical, legal and social concerns, the
application of stem cell research in drug discovery and development
is set to play a greater role as areas of unmet medical needs will
need to be addressed as rates of incidence...
The possibility of a new class of anti-inflammatory compounds that
exhibit broad action across multiple therapeutic sites could be on
the horizon after Reata announced the completion of a license
agreement for these drug candidates...
Olympus launches its latest screening station for the life science
industry, in which the design aims to combine the modularity and
flexibility of a microscope-based set-up with the automation and
throughput of screening applications.
Scientists have made a remarkable discovery that could open up new
avenues in drug development resulting in novel therapies for the
treatment of poxviruses such as variola virus, the cause of
smallpox.
Outsourcing outfit, Oxford Genome Sciences and the University of
Oxford have announced the development of new clinical biomarkers
for colorectal cancer, which paves the way for a more personalised
approach in treating this killer...
Ablynx and Procter and Gamble have announced the extension of its
Nanobody drug discovery and development agreement to metabolic
targets in a move that reinforces the feeling within the industry
regarding Nanobody technology and its...
Sigma-Aldrich launches an online tool consisting of data detailing
biological pathways that provides an online resource to those in
the drug industry interested in first-in-class range, including
small molecules, antibodies, enzymes,...
Olympus has unveiled a working concept of what is claimed is the
next generation in fluorescence in vivo imaging systems by enabling
time-lapse and live imaging of emitted light from labelled
processes and tissues.
Beckman Coulter launches its latest monoclonal antibody that
identifies Tolereogenic cells making it highly in transplant and
cancer research. It is also applicable in clinical research on
autoimmunity.
VASTox has initiated a fifth drug discovery programme for cancer
focusing on a crucial pathway that is active in the developing
embryo when cells are required to constantly grow and
differentiate. The pathway has been identified as...
Wyatt Technology launches its newest addition to its Multi-Angle
Light Scattering (MALS) Detector range, boasting twice the signal
to noise ratio and 100x the dynamic range of previous Wyatt's
miniDAWN instruments.
For the first time in its 30-year history, the biotechnology
industry in 2005 surpassed $60bn (€49bn) in revenues according to
Ernst & Young's 2006 Global Biotechnology Report, an astounding
growth considering that in 1996...
Tapestry has presented data that supports the oral bioavailability
and antitumour activity of its drug candidate designed to overcome
multi-drug resistance in solid tumours that have become resistant
to taxane therapy.
The UK's Medicines and Healthcare products Regulatory Agency (MHRA)
has said it has so far found no evidence of wrongdoing in the human
trials of the monoclonal antibody TGN1412, which US contract
research firm Parexel carried...
After branching out of the US with the opening of new facilities in
Singapore and India and a recent Eastern European acquisition,
US-based Albany Molecular Research (AMR) used Interphex 2006 to
highlight its new range of global services.
Nastech Pharmaceuticals presents data demonstrating the
effectiveness of its small interfering RNA (siRNA) therapeutics to
target and inhibit influenza viral production, which is certain to
have useful applications against current...
Scientists in the US have found out how the enzyme helps initiate
the process that leads to colorectal cancer. Their discovery of a
new molecular mechanism by which an enzyme promotes cancer spread
may provide a new target at which...
A new report out today has revealed that the uptake of assays for
in-vitro diagnostics is being hindered due to a lack of knowledge
of this technology, in which its high sensitivity, specificity and
fast turn-around times has proved...
A leading scientist believes that cosmetic considerations and a
lack of patent opportunities is stopping the pharmaceutical
industry from investing in the development of a new therapy proven
to be effective in the treatment of MRSA.
Scientists have made a breakthrough in their research that may
change the way inflammatory conditions are treated by focusing on
certain nerve cell receptors in the brain that control inflammation
in the body.
Agilent has upgraded its GeneSpring GX 7.3 gene expression
informatics software, giving it new features designed to allow
researchers to understand faster what their results really mean.
ExonHit and bioMirieux have announced that scientific data
generated in the detection of breast cancer could well lead to the
development of novel diagnostic tests that will enable the early
detection of breast cancer from blood.
Despite the technological breakthroughs that have enhanced the
R&D capabilities of pharmaceutical companies, drug research and
development is facing a major problem as R&D productivity in
the last decade is at a historical...
Upstate and Cisbio have announced the launch of an assay for
Serine/Threonine kinase screening that offers simplified kinase
assay development, which allows for profiling and high-throughput
screening (HTS) on a large range of Ser/Thr...
Scientists have discovered the existence of a HIV accessory protein
that disables host immunity via receptor-protein intermediary in a
discovery that points to possible novel ways to fight AIDS, immune
disorders and sepsis.
Affymetrix introduces its new ChIP-On-Chip array product line that
its designers hope will provide drug researchers with new
whole-genome tools to assist scientists discover DNA-Protein
interactions.
New diabetes trials scheduled to start this spring have been
heralded as groundbreaking as researchers aim to reverse juvenile
diabetes of which numbers have been steadily on the rise in
developed nations.