Scientists have made available a powerful new tool for studying
brain development, which will help scientists discover the genetic
origins of brain cancers, which could speed development of novel
drugs to treat them.
Researchers have discovered a series of enzyme inhibitors that
appear to block the replication of the SARS virus - a finding that
could help speed up the research and development of drugs used to
treat the killer virus.
According to a new report, the pharmaceutical market grew seven per
cent, to $602 billion (€501 billion) in 2005. The report
highlighted the emerging markets including China, Korea, Mexico,
Russia and Turkey, which experienced double-digit...
BioTrove and Blue Sky Biotech announce a collaborative effort to
provide a unique service solution, utilising mass
spectrometry-based high-throughput screening assays on previously
unscreenable drug targets.
The European Union has approved new alternatives to animal testing
of drugs and chemicals, which will not only reduce the number of
animals needed for testing, but will also increase the accuracy of
the tests, thereby making the products...
Vertex Pharmaceuticals Incorporated and Cystic Fibrosis Foundation
Therapeutics, (CFFT) have announced they have entered into a
collaboration to develop a novel, oral drug candidate for the
treatment of cystic fibrosis (CF).
An innovative technology derived from plants, which is designed for
the production of new pharmaceuticals is to form the basis of a new
company that is to focus on (bio)pharma firms involved in the
discovery, development, production,...
Shimadzu have introduced its latest emission spectrometer, which
has been designed for use in pharmaceutical research and
development whilst reducing reduced running-costs and high
sensitivity and low contamination.
Researchers have constructed a model of an axon, which they have
used to reproduce a change in the axon's shape that is
characteristic of neurodegenerative disorders. The model provides a
new road to discovering new kinds of...
Drug discovery outfit, Tripos, has announced details of a
collaboration with Abbott, which is to concentrate on chemical
design and synthesis in a deal that mirrors, those announced
earlier in Q1 with Genzyme, GSK Research and Development...
NicOx and Merck have signed an agreement to collaborate on the
development of new antihypertensive drugs. The agreement follows
the successful completion of the companies' research collaboration,
which has generated promising...
Researchers in the UK think that knowledge of 'movement routes' is
the key to predicting patterns of spread of infectious diseases in
humans, which would enable scientists to administer effective drug
therapies that are...
Thermo has upped the stakes at the Pittcon exposition taking place
this week in Orlando by unveiling QuickQuan, a fully automated,
high-throughput software solution for the analysis of chemically
diverse compounds, speeding up the...
ChemAxon and FMC has announced a global all product license
acquisition of ChemAxon's complete product line and the switching
over to JChem cheminformatics platform.
Bayer Healthcare has selected Genedata's Bioinformatic platform for
its target research and biomarker activities in which the deal will
involve the mechanistic analysis of cardiovascular and cancer
biomarker genes.
German drug maker Schering has rejected Merck's unsolicited
takeover offer of €14.6 billion ($17.4 billion), claiming the deal
undervalued the company.
Bruker Daltonics announces the release of its MALDI Molecular
Imager, a system for in-vitro imaging of peptide and protein
biomarker distributions in tissue sections and cell clusters. The
imager addresses the need for high-sensitivity...
A member of a new class of drugs may increase survival in patients
with myelodysplastic syndrome (MDS), and could become the new
standard of therapy for this group of pre-cancer disorders, said
researchers.
Kreatech has launched the first complete miRNA isolation and
labelling kit, which combines the upstream isolation of small RNA
and the reagents necessary to label these DNA samples for
microarray analysis, offering a more complete...
A new method has revealed that a discovery involving menthol could
point towards new therapies to treat chronic inflammatory and
neuropathic pain indications by targeting the temperature-activated
ion channels.
FEI and Sidec have entered into an agreement to commercialise a
range of Protein Tomography solutions that could provide drug
companies with services that could increase the chances of success
in early stage drug development.
Researchers in the US think they have identified a compound that
interferes with the pathogenic effects of Huntington's disease that
could lead to the development of a new treatment for the disease as
well as making an impact...
VGX and Dowpharma have signed an agreement to advance the
development of a novel cancer compound currently in pre-clinical
development that initial clinical studies will target individuals
with Non-Hodgkin's Lymphoma.
Nucryst Pharmaceuticals has been granted a new patent that covers
the company's proprietary nanocrystalline silver for use in the
treatment of acne. This latest addition strengthens the company's
patent portfolio, which...
Stem Cell Sciences have launched the first complete, defined medium
that enables the large-scale, consistent production of mouse ES
cells. The announcement closely follows the formation of an
exclusive agreement completed last year...
Agilent introduces its next generation of assay kits for its 2100
Bioanalyser Lab-on-a-Chip platform that aims to replace
labour-intensive SDS-PAGE and capillary gel electrophoresis (CGE)
methods providing faster microfluidic analyses.
A new study has revealed the existence of new drug targets for
tuberculosis (TB) treatments, which could essentially dictate the
design of TB drugs of the future. The bacterium that causes TB
currently infects one person in three...
Velocity11 make available a benchtop microplate handling system
that claims to provide the features and flexibility of much larger
and more expensive automation platforms.
A newly discovered process that explains how the body's nervous
system relays information, may depend on how "wet" the "kiss" is
when one neuron fires a packet of neurotransmitter across a synapse
to a receptive...
New research has suggested only seven per cent of drug applications
for treating people with rare diseases were approved in Europe
between 2000 and 2004, despite the fact that there are currently
more than 5,000 conditions needing...
Applied Genetic Technologies Corporation (AGTC), announced today
the initiation of a Phase 1 clinical study to test the safety of
AGTC-0106, its investigational gene therapy product for patients
with Alpha-1 Antitrypsin deficiency...
GE Healthcare has announced the introduction of Ettan nanoLC, a
fully bio-inert, robust, nanoscale peptide separation system that
delivers highly reproducible performance and is ideal for 1D-liquid
chromatography (LC) proteomics applications...
Scientists have discovered a new way that drugs can attach
themselves to DNA, providing a crucial step forward for those who
are developing drugs to combat cancer and other diseases. The
breakthrough heralds a new way of recognising...
Scientists have found that certain T-cell stimulation could help
improve treatment of autoimmune disease and cancer, which could be
significant for developing new drug treatments to help patients
with autoimmune diseases such as rheumatoid...
Nastech Pharmaceutical Company, announced today the expansion of
its RNAi therapeutics pipeline by initiating an RNAi therapeutics
program targeting influenza and respiratory diseases.
Isis Pharmaceuticals and Rosetta Genomics has announced a joint
research collaboration to develop microRNA related therapies for
the treatment of liver cancer, demonstrating the therapeutic
potential of microRNA as a drug target...
Graffinity, announced today that it has entered into its second
research collaboration with Mutabilis, which aims to discover novel
therapeutics for infectious diseases, building on 2003's
collaboration focusing on another anti-infective...
An experimental TB drug has proved effective against multi
drug-resistant forms of the disease as well as becoming the first
compound to treat the latent stage of this disease, which affects
nearly a third of the world's population,...
Celera Genomics has announced that Abbott has selected two
additional cancer targets for further development, which brings the
total of targets to four under investigation as a result of the
collaboration between the companies to...
Rigel has completed the Phase I stage of its drug interaction study
in patients with rheumatoid arthritis. The oral syk kinase
inhibitor could be an improvement over current treatment options,
which have side effects that include...
Researchers have isolated a protein molecule that may hold the key
to learning and memory disorders that have been linked with autism.
By isolating this potential drug target, new therapies for diseases
in which synapses either...
Thermo Electron makes available a new datasheet to provide an
overview of the capabilities of its Watson Laboratory Information
Management System (LIMS), which is designed to support drug
metabolism and pharmacokinetic (DMPK) studies...
A consortium of US scientists have developed and evaluated a robust
new system for analysing how drugs bind to proteins, which could
speed up the delivery of potential new drugs and improve existing
ones.
Biofusion has announced the creation of Genophrenix, a new spin-out
company that aims to focus on treatments originating from
biochemical pathways implicated in a range of neuropsychiatric
diseases, including schizophrenia.
Asynt have launched the first affordable 500ml parallel reactor on
the market with its latest addition to the DrySyn range, providing
a safe and flexible alternative to oil bath and mantles.
A unique DNA-based targeting technology has shown to halt tumour
progression with significantly smaller chemotherapy doses opening
the way to reduce the side effects as well as increase the efficacy
of anti cancer therapies.
A natural compound could become the starting molecule for the
design of drugs that prolongs lifespan and delay the onset of
aging-related traits in vertebrate organisms, supporting the
potential utility of the compound in human aging...
A consortium of researchers has detailed the activity of a novel
drug compound that kills multiple HIV strains via a unique
mechanism of action. The discovery brings with it hope in using
this compound in both topical and systemic...
Swiss pharma giants, Novartis has formed a collaboration with
Alnylam, which aims to develop an RNAi-based therapeutic for
pandemic flu. The deal is in response to analysts who believe that
current vaccines and existing anti-viral...
Contract Research Organisation (CRO) Averion, and the SIPLAS
Research Organisation has signed an agreement to provide promotion
and support of clinical trials in a move that that reinforces Latin
America as an emerging hub of clinical...