Sigma Aldrich has launched a new integrated lysis and affinity
purification (iLAP) column, which greatly simplifies the process of
cell lysis and histidine-tagged protein purification into one step,
allowing fast, efficient and non-denaturing...
AIDS researchers have uncovered new evidence, which points to the
'fitness' of the HIV virus as a primary factor in explaining
different resistant patterns to the drugs that treat the disease.
A new report reveals that a lack of validation amongst drug
discovery processes has emerged as a major restraint to the uptake
and penetration levels of computational biology tools in the drug
discovery industry.
Scynexis Europe is to operate under the name Selcia after Scynexis
sold its subsidiary in the United Kingdom to its UK management in a
move that allows Selcia to provide custom radiolabeling, chemistry
and analytics services to a...
New drugs that are based on a compound found in the body may give
renewed hope to stroke victims and sufferers of degenerative brain
diseases such as Alzheimer's as researchers are hopeful of a new
therapeutic approach.
Pfizer has announced the expansion of an existing collaboration
with Sangamo Biosciences, which will use zinc finger DNA-binding
protein (ZFP) technology to develop additional cell lines for
enhanced protein production.
NanoDrop Technologies has introduced new software for the NanoDrop
ND-1000 UV/Vis Spectrophotometer, which aims to make it an even
more powerful and convenient tool for measuring 1 ul samples.
Velocity11 has announced a new configuration of its BioCel
sample-processing platform that will allow all cell-based Elisa
procedures to become fully automated, reducing the risk of human
error, contamination and time spent on tedious...
UK's Pharmagene has joined forces with US company Asterand to form
a human tissue supply and research services company that will
dominate the pharma industry. The merger, which was finalised last
week, will also solidify Pharmagene's...
Research undertaken by Nastech has uncovered that endothelial tight
junctions play a role in atherosclerosis, which may provide new
therapeutic targets for cardiovascular disease.
With two acquisitions in two months, US biotechnology major Genzyme
has strengthened and diversified its ability to develop gene
therapy products that use either adenovirus or adeno-associated
virus vectors.
The expiration of the Polymerase Chain Reaction (PCR) patent is set
to offer growth opportunities for nucleic acid purification and
amplification technologies, particularly for small companies, who
can offer tests without developing...
A recent study highlights the importance of a new a target for
taste modulation that could be the key to helping drug
manufacturers mask bitter, unwanted tastes that turn many people
off their medicines.
The threat of antibiotic resistance reared its ugly head again
after US researchers found that the most common antibiotic
treatments do not work in a significant number of cases, leading
for calls to find viable alternatives to ageing,...
A new report warns that as nanotechnology becomes a reality, Europe
must not miss the boat, and raises the alarm that the potential
benefits of nanomedicine in Europe will be lost without major
investment in R&D.
A group of researchers think they have cracked the gene code behind
a key family of fungi, which includes the leading cause of death in
leukaemia and bone marrow transplant patients. The genome discovery
could help combat disease...
Thermo Electron has unveiled its latest Laboratory Information
Management System (LIMS), its latest evolution in
commercial-off-the-shelf (COTS) laboratory information management
systems for pharmaceutical manufacturing R&D...
Affymetrix has launched its latest microarray sequencer, which
enables researchers to identify genetic variations associated with
diseases, forensics, population studies or stem cells, proving
particularly useful in drug research...
Wyeth are to establish a Bio-therapeutic Drug Discovery Research
Facility in Dublin in a move that adds to Wyeth Grange Castle
Campus in Ireland's capital and reinforces the growth of Ireland's
biotechnology research and...
The breast cancer therapeutics market is expected to show sustained
growth and opportunity for new market participants as greater
efficacy and reduced toxicity of innovative breast cancer therapies
increase their uptake.
BioGenetics Capital announced that it has closed a $5.5 million
financing round with Contract Research Organisation (CRO) Services
Group, Clinquest Group, in a move that gives the company access to
the fast-growing life sciences markets...
Tripos has announced the latest details in its cost cutting
strategy, which is expected to result in job losses, principally in
the UK. The cuts come as Tripo's four-year $90 million file
enrichment project with Pfizer draws...
Cresset Biomolecular Discovery has launched a technology that
identifies the 3-dimensional bound conformation of hits and
potential drugs in a biological target, assisting scientists
involved in ion channel research.
Artel, has announced that the International Organisation for
Standardisation (ISO) has approved the use of the photometric
method for liquid delivery performance verification, which
emphasises the role photometry has to play for drug...
DOV Pharmaceutical has announced the initiation of a Phase Ib
clinical trial, which investigates the potential of its triple
reuptake inhibitor candidate for treating depression. The drug's
mechanism of action inhibits three...
The latest research included in the proceedings of the Interscience
Conference on Antimicrobial Agents and Chemotherapy (ICAAC) means
that antibiotic treatments and management therapies feature
strongly in DrugResearcher’s round-up...
MiraiBio has released software for the statistical analysis of
multiplexed data generated on its liquid array detection system, a
platform that is designed for immunoassay, enzyme function, and
receptor-ligand interaction applications,...
Latest data by La Jolla Pharmaceuticals indicate the potential of
novel, orally active small molecule inhibitors of a central enzyme
may provide clinical benefit for the treatment of stroke,
ulcerative colitis, and other autoimmune...
New insights into the dysregulation of beta cells and their impact
on type 2 diabetes progression is now possible after Roche
announced a partnership, which aims to identify novel pathways and
new biomarkers for drug development.
The first diagnostic test available for the confirmation of chronic
sinusitis (CS) disease has been made available by Accentia
Biopharmaceuticals, which will assist in the identification of a
problem that affects an estimated 31 million...
Thermo Electron Corporation, have added to its crystallisation
range with the new compact, entry-level, TableStore, which enhances
protein structure and drug discovery investigations by offering
optical clarity and automated storage...
Solexa has announced the introduction of its DNA sequencing,
expression profiling and micro-RNA analysis platform designed to
generate over a billion bases of sequence per run, making it ideal
for plans to sequence the entire human...
A new therapy for Parkinson's disease involving brain implants has
been developed by US scientists, who believe this new treatment is
a viable alternative to drugs currently used to treat this chronic
irreversible brain condition.
CuraGen and TopoTarget have announced preliminary data suggesting
its small molecule candidate may have potential anti-tumour
activity against haematologic cancer.
US drug company, Eli Lilly, offered a more encouraging outlook than
was expected forecasting an earnings growth of up to 12 per cent, a
stark contrast to its struggling competitors, who also face generic
competition, drug safety and...
Clontech has announced a new addition to its TALON chemistry range,
which uses magnetic bead technology to separate microscale
quantities of protein when placed on a magnetic separator.
According to a new report, 2006 will be a crunch year for companies
that have expiring product patents looming. With generics
increasingly penetrating the market, this has thrown into doubt the
growth of this industry in the foreseeable...
GE Healthcare has announced the availability of its single-use spin
column designed for purification of histidine-tagged proteins using
a standard microcentrifuge. It saves researchers time as it
achieves direct protein purification...
Phoqus has announced it has commenced Phase I of a clinical study
researching its experimental treatment, which could become the
first Circadian endocrine treatment for adrenal insufficiency.
Domantis has announced an alliance with pharma giants Bristol-Myers
Squibb to develop human Domain Antibody (dAb) products, a novel
approach to address therapeutic targets involved in T-cell
co-stimulation.
The question as to why some cancers resist drugs could be answered
by the discovery of new mechanisms, which delve deeper into how
cancer cells evolve to become resistant to various chemotherapy
drugs.
A dairy based vaccine could soon be on the horizon after
researchers took a giant step in the development of a series of
effective cancer-fighting vaccines that appear to be able to stop
and reverse cancer growth.
Stratagene announces a molecular diagnostics agreement, which aims
to focus on the growing molecular diagnostics market for infectious
diseases, currently worth $6.5 billion (€5.5 billion), expanding to
$12 billion by 2010 driven...
Researchers believe that they have identified a drug target
molecule that could be used to treat mental impairment in people
with Down's syndrome paving the way for a treatment that could
improve the quality of life for sufferers.
Clinical research organisation, Covalent Group, has agreed with
Emergent BioSolutions to develop immune globulins for treatment
exposure of anthrax infection, signifying another step in the
worldwide drive to bring an effective treatment...
Researchers believe that new treatments or ways to diagnose memory
problems will get a boost from a substantial grant that aims to
create a brain-scanning method to test drug treatments, which
investigates how brain cells age, and...
Roche and BioCryst Pharmaceuticals announced an agreement to
develop and commercialise BioCryst's phase I compound, which has
been developed for the prevention of acute rejection in
transplantation and for the treatment of autoimmune...
Gentra Systems has introduced its new versaGene DNA Cell
Purification Kit, which responds to the growing need for
high-quality DNA for sensitive downstream applications. The kit
uses chemistry and column design to purify DNA with...
Oxford University has been given the go-ahead to resume building
work on its new animal research laboratory complex, which had
previously been the subject of protest from animal rights activists
last summer.
Bayer Diagnostics launches its latest immunoassay system, part of
its ADVIA family of automated clinical laboratory solutions, which
enable laboratories to rapidly perform a wide variety of
disease-specific tests which enhance the...