A whole new generation of drug treatments and therapies for stroke,
migraine, Alzheimer's and other brain disorders could be created
after the discovery of a mechanism for regulating brain blood flow
was made by researchers.
A new method to improve the accuracy and speed of protein
visualization has been developed. The technique, which uses a novel
set of biosensor dyes, promises to dramatically increase the
accuracy and speed of the technique, used in...
Research into many human diseases and its corresponding drug
treatments will be made easier after an innovative new method to
expand mouse T cells without autologous antigen-presenting cells
and antigen was launched by Dynal Biotech.
Inproteo and its subsidiary company, Prosolia, have announced a
licensing agreement with Thermo Electron Corporation for its
ElectroSonicSpray Ionization (ESSI) Technology. The move attempts
to commercialize the ESSI technology, gaining...
Newly discovered serotonin pathways in the nervous system are
providing a path toward future pharmaceutical treatments for
depression and other disorders such as depression, anxiety, sudden
infant death syndrome, attention deficit...
TransTech Pharma and Merck has announced a $26 million research
collaboration using TransTech's proprietary TTP Translational
Technology to discover and develop novel small molecules for a
therapeutic target of interest to Merck.
A collaboration agreement to identify and develop an improved
variant of CT500, a non-antibody protein with antagonist activity
against HMGB1 has been established, paving the way for
applications, to treat tumours and autoimmune diseases.
An updated version of a database that details GPCR and
ADME/Drug-Drug Interactions has been released by Aureus Pharma who
believe this system will prove invaluable in identifying,
validating and prioritise new targets and ligands...
The first natural human model for specific Hodgkin's and
non-Hodgkin's lymphomas has been identified by scientists whose
studies into cancer immunity in chickens could pave the way for an
effective drug therapy to treat...
GlaxoSmithKline are to commission the pharmaceutical industry's
first in-house Accelerator Mass Spectrometry (AMS) facility, with
the primary aim of providing information on human metabolite
formation of new drug candidates and...
The pharmaceutical industry has announced it would introduce a
central, accessible database to improve the communication of the
clinical study results of marketed drugs.
Researchers studying cell migration and the screening of drug
compounds, can benefit from a new cell analysis system developed by
Guava Technologies which places an emphasis on cell health
profiling that is essential in the field...
UK Life Sciences Company Genetix has launched a new hybrid bed
option designed to compliment its high-throughput, fully featured
QArray microarrayer platform used to detect low-level expression of
genes making it ideal for all microarray...
Enanta Pharmaceuticals has announced the initiation of Phase 1
clinical trial of its new antibiotic candidate, EP-013420, a first
in its class Bridged Bicyclic Ketolide (BBK) antibiotic that could
prove effective against respiratory...
GlaxoSmithKline (GSK) is facing a number of US lawsuits, which
claims the company had covered up negative data that indicated its
antidepressant Paxil might increase suicidal tendencies in young
people.
The world's first commercialised genetic test for determining
intracontinental subpopulation (ethnic) admixture of individuals
could lead to the development of more specific, better-tolerated
and more effective drugs in the future.
Dharmacon, supplier of RNA and RNAi research products, has launched
a range of siRNA reagents for its siGenome human siRNA collection,
which supports all phases of research ranging from functional
genomics and initial drug target...
A study, which compares the use of colormetric versus infrared
detection for reverse-phase protein microarrays, concludes that the
emergence of this infrared technology brings significant advantages
to reverse phase array analysis.
A new approach to treating obesity which blocks brain signals that
control cravings has shown promising results in human subjects
during advanced clinical trials paving the way for further testing
and an eventual launch date.
A team of researchers has issued a plea that that
microarray-derived gene expression data should be available in a
public repository in the same way that gene sequence data is
collated for use by all.
Labtronics has launched the latest addition to its Nexxis LAB suite
of products, promising complete automation to a whole host of
manual procedures as well as security features that make it ideally
suited to the controlled pharmaceutical...
Scientists have discovered a highly effective method to produce
novel aminocoumarins, antibiotics that are useful in the fight
against drug-resistant bacteria that could represent a new
antibacterial class to tackle the growing problem...
The spending for Pharmaceutical-Biotech capital and maintenance
projects in the public and private sectors approached $13 billion
in 2004 (€10.7bn), but companies are often delaying site decisions,
with promises of fast-track permitting...
Researchers have claimed proteome mining could make the discovery
and development of cancer, hypertension, diabetes, inflammation and
infectious disease drugs enormously more effective, fast tracking
protein targets that can be tested...
Scientists have determined the precise molecular structure of a
potential new target for treating prostate cancer, a disease driven
in part by abnormal testosterone activity, which affects one in six
American men.
GlaxoSmithKline (GSK) became the first major drug maker to disclose
details of its clinical drug trials effectively settling a lawsuit
filed by the New York state attorney general, Eliot Spitzer, who
accused them of concealing information...
A leading consultancy firm has predicted the use of radio frequency
identification (RFID) within the pharmaceutical industry could
prevent most of the 1.25 million adverse reactions and 7,000
patient deaths annually in the United...
A novel, non-radioactive, quantitative cell-based assay, which uses
the In-Cell Western technique, has determined the functional
potency of agonists and antagonists for D2 and D3 receptors,
allowing drug researchers to quantify multiple...
The European Union has granted nearly €25 million to two
large-scale research projects coordinated by the University of
Helsinki in the area of protein kinases, a promising class of new
drug targets.
A new information database consisting of genes associated with
multidrug resistance in cancerous tumours has been created which
identifies transport protein expression and drug resistance in
cancer cells.
Guava technologies have introduced two new turnkey assays for their
suite of personal cell analysis systems, which intends to make drug
discovery applications in the areas of immunology and oncology more
sensitive and accurate.
The discovery of a naturally occurring protein could play a pivotal
role in the fight against autoimmune diseases with the possibility
of developing this compound into a practicable treatment for
rheumatoid arthritis (RA), which currently...
French pharmaceutical group Sanofi-Synthelabo on Friday formally
announced the birth of Sanofi-Aventis, the world's third-largest
pharmaceutical company, ranking number one in Europe.
Bio-Rad has completed its purchase of MJ GeneWorks, the parent
company of DNA analysis specialist MJ Research, for $32 million,
well short of the $47 million originally forecast.
Researchers in the US and Austria have developed a method that
could vastly improve the ability of atomic force microscopes to
visualise the chemical composition of a sample, follow variations
of the sample, as well as map its topographic...
In a joint project with the Max-Planck-Institute for Molecular
Genetics, Germany's Scienion is adapting its nucleic acid chip
technology to handle protein applications. The project aims to
develop antibody chips for the analysis...
In an open letter to the British medical Journal, the director of
the UK Cochrane Centre Sir Iain Chalmers has added his voice to
those calling for complete disclosure of clinical trials by
pharmaceutical companies.
Two-dimensional (2D) gel electrophoresis can be time-consuming and
labour intensive, but its value to proteomics research means that
the market for these products will more than double by 2010.
Sigma-Aldrich and Caliper Life Sciences have teamed up to develop
and co-market a series of automated systems for a wide variety of
applications in genomics, proteomics, and drug discovery.
Scientists in the UK and Germany have discovered that drugs that
inhibit enzymes known as metalloproteinases have the hallmarks of a
new treatment for the common skin diseases psoriasis.
Pipetting technology company CyBio has posted half year sales of
€4.5m, down slightly on the €4.6m in 2003. This muted sales
performance is attributed to the differing development of business
in CyBio's sales regions.
Netherlands-based Qiagen achieved organic growth of 32 per cent for
the second quarter of 2004, but profits fell by a fifth as the cost
of restructuring took its toll.
Imaging Systems Company, Richardson Technologies, are to showcase
its Real Time Microscope (RTM), a radical imaging system capable of
providing real time, full colour images, providing improved sample
detail, essential for pharmaceutical...
Elchrom Scientific introduces a novel purification technology
enabling a greater yield of ultra pure siRNA synthetic
oligonucleotides at a faster turn around rate, rapidly increasing
siRNA oligonucleotides (oligos) quantity required...
The first ever application to start clinical trials of a
therapeutic based on small interfering RNA (siRNA) - for the wet
form of the eye disease age-related macular degeneration - has been
filed by Acuity Pharmaceuticals.
Researchers at Newcastle's Centre for Life have been given the
go-ahead to create stem cells from unfertilised human eggs, thought
to be the first time that such a license has been granted in
Europe.
Fisher Scientific has completed its €3bn merger with Apogent
Technologies, continuing an acquisitive period which has seen it
become one of the top companies in the market for research tools.
German biotech company Evotec OAI boosted its second quarter
revenues by 18 per cent to €17 million, despite the difficult
operating environment for companies supplying drug discovery
technologies, continuing its recovery from a weak...
Absolute Vision of the UK has unveiled a new hand-held code reader
that can be used for conventional barcodes, the new reduced space
symbology (RSS) code and two-dimensional data matrix markings.
